Protein Alignment Grd and gabrr3a

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001122232.1
• Gene: gabrr3a / 570876
• ZFINID: ZDB-GENE-080722-20
• Length: 472
• Species: Danio rerio
• Alignment Length: 652
• Identity: 171/652 - (26%)
• Similarity: 265/652 - (40%)
• Gaps: 206/652 - (31%)

  Fly    42 LISCCLLMLCIYPNAWPWSI----GPGSGPFSVSADSIKGRGDTHRLG---EMGTSLSSSLPSSW 99
            |....|.::|:   ||.|.:    |..:.......|...|....|:.|   :..|..|.| ..|.
Zfish     3 LALAALRLMCL---AWLWPVAWLKGSNTQNQRRHKDVYLGENTKHKFGGRIDFKTKKSDS-TKSL 63

  Fly   100 LTQSNNHANISELLDNLLR--GYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQ 162
            |.:|          :.|||  .:|.::||.|||....:.:|:.|.|:..||||:|.::|..|.|.
Zfish    64 LIKS----------EQLLRIEDHDFAMRPGFGGSAIPVGIDVQVESIDGISEVNMDFTMTLYLRH 118

  Fly   163 SWVDKRLAFEGAQD-TLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSR 226
            .|.|.||||..:.: :......::.:||.||.:|.:.|:|::|..|..|..:|::.:|.:|||.|
Zfish   119 YWQDDRLAFPSSNNKSRTFDARLVKKIWVPDVFFVHSKRSFIHDTTMENIMLRVFPDGNILYSVR 183

  Fly   227 LTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAG 291
            :|:.|.|.|:.:.||:|.|.|.|:..|:.|..:|::..|......:. .:::.||||
Zfish   184 ITVTALCSMDFSRFPLDTQNCSLELESYAYNENDLMLYWKNGNDSLR-TDEIALSQF-------- 239

  Fly   292 NLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATG 356
                                                                             
Zfish   240 ----------------------------------------------------------------- 239

  Fly   357 GSGSTTGLSGTITLETNHPSE----------YSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWV 411
                        .:|..|||.          |:.|.:||.|:||:..|::|.|.|..|:|:||||
Zfish   240 ------------FIEEFHPSYGLAFYSSTGWYNRLYINFILRRHIFFFMLQTYFPTMLMVMLSWV 292

  Fly   412 SFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVH 476
            |||::|.|...||||||||||||:.:.......:|:|||..|:|.:::.||.|:|.:::::|.|:
Zfish   293 SFWIDRRAVPARVSLGITTVLTMSTIITGVSASMPQVSYVKAVDIYLWASFLFVFLSVIEYAAVN 357

  Fly   477 YYTKYGSGECYFIIEELDS-ESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGML 540
            |:|         .:||:.. :.|:.   |.:.|   :|::..|:
Zfish   358 YFT---------TVEEMKKLQKGKL---PASYD---ATQAMAYD--------------------- 386

  Fly   541 TSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAA 605
                                |.|              .|:.|...   ..|.|||.:......|.
Zfish   387 --------------------GCF--------------HDDIDASP---FPELPTTPSTTRTIPAR 414

  Fly   606 AQAARISPPTGGRRRMSYYRREEMEARRKGK--RTPQYNSVSKIDRASRIVFPLLFILINVFYWY 668
            |.:.. .|||.|.|   .:|:     |..||  |....||. .||..|||:|||.::|.|:.||.
Zfish   415 ASSTE-PPPTEGTR---LWRK-----RSVGKNIRFIMSNSY-MIDSYSRILFPLAYLLFNIIYWC 469

  Fly   669 GY 670
            .|
Zfish   470 IY 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	60/218 (28%)
		LIC	111..670	CDD:273305	153/574 (27%)
		Neur_chan_memb	398..667	CDD:280999	78/271 (29%)
gabrr3a	NP_001122232.1	LIC	67..471	CDD:273305	154/582 (26%)
		LGIC_ECD	88..272	CDD:355788	61/269 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810