Protein Alignment Grd and gabrr2b

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_697486.2
• Gene: gabrr2b / 569032
• ZFINID: ZDB-GENE-041014-174
• Length: 464
• Species: Danio rerio
• Alignment Length: 632
• Identity: 176/632 - (27%)
• Similarity: 268/632 - (42%)
• Gaps: 172/632 - (27%)

  Fly    41 LLISCCLLMLCIYPNAWPWSIGPGSGPFSVSADSIKGRGDTHRLGEMGTSLSSSLPSSWLTQSNN 105
            |.:...|.:||        :|..| |....|......:...|     ||.|...:    |.::..
Zfish     4 LFLKAALFVLC--------AIAEG-GKMKYSLRRTNPQNHKH-----GTPLFKKM----LDETKT 50

  Fly   106 HANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLA 170
            ||..||.|.: :..:|.::||.|.||...:.||:.|.|:..||||||.::|..|.|..|.|:||:
Zfish    51 HAVKSEHLLS-VEDHDFTMRPAFAGPAVPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLS 114

  Fly   171 FEGAQD-TLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCP 234
            |....: ::.....::.:||.||.:|.:.|:|::|..||.|..:|:|.:|.||||.|:|:.:.|.
Zfish   115 FPSKHNKSMTFDGRLVKKIWVPDVFFVHSKRSFIHDTTTENIMIRVYPDGHVLYSLRVTVTSACN 179

  Fly   235 MNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVYK 299
            |:.:.||:|.|.|.|:..|:.||..|::..|......::..:.:.||||            ::.|
Zfish   180 MDFSRFPLDTQTCTLELESYAYTDEDLMLYWKSGDESLSTDDKISLSQF------------LIQK 232

  Fly   300 AAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTGL 364
                      |:.      ||::                        ||          .|:||.
Zfish   233 ----------FHT------TSRL------------------------AF----------YSSTGW 247

  Fly   365 SGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGIT 429
                         |:.|.:||.|:||:..||:|.|.|..|:|:|||||||::|.|...|||||||
Zfish   248 -------------YNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 299

  Fly   430 TVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEELD 494
            |||||:.:.......:|:|||..|:|.::::||.|:|.::|::|.|:|.|....|
Zfish   300 TVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVHDG---------- 354

  Fly   495 SESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMKL 559
                              |:.|:.:......|.||    ..|..||        |..:|
Zfish   355 ------------------TDRKLRQKTLPGTCDIS----SMRTMML--------NEAYG------ 383

  Fly   560 LGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARISPPTGGRRRMSYY 624
                         |.||:......||.:.:.|      .|......|....|.|...|.::.:.
Zfish   384 -------------RPDSNGLAGYTQTTVSSEE------PAEKQDPIAVCLSIGPEVKGAKKRTL- 428

  Fly   625 RREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYL 671
                     :|.|..|  :...||..||::||..||..|:.||..||
Zfish   429 ---------RGLRIIQ--NTHAIDAYSRMIFPGAFIFFNLIYWSVYL 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	68/216 (31%)
		LIC	111..670	CDD:273305	158/559 (28%)
		Neur_chan_memb	398..667	CDD:280999	74/268 (28%)
gabrr2b	XP_697486.2	LIC	55..463	CDD:273305	159/560 (28%)
		Neur_chan_LBD	56..261	CDD:280998	78/280 (28%)
		Neur_chan_memb	268..460	CDD:280999	74/268 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810