Protein Alignment Grd and gabrb3

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_005166136.1
• Gene: gabrb3 / 566922
• ZFINID: ZDB-GENE-101102-2
• Length: 532
• Species: Danio rerio
• Alignment Length: 602
• Identity: 171/602 - (28%)
• Similarity: 256/602 - (42%)
• Gaps: 159/602 - (26%)

  Fly   101 TQSNNHANIS---ELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQ 162
            |.:|...|:|   |.:|.||:|||..:||||||.|..:.:.|.|.|:..:|||:|.|::..||:|
Zfish    60 TSANEPGNMSFVKETVDKLLKGYDIRLRPDFGGAPVAVGMSIDVASIDMVSEVNMDYTLTMYFQQ 124

  Fly   163 SWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRL 227
            .|.|||||:.|....|.|...:..::|.|||||.|.|:|::|.:|..|:.:|::.:|.|||..|:
Zfish   125 YWRDKRLAYTGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRI 189

  Fly   228 TIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGN 292
            |..|.|.|:|..:|:|.|.|.|:..|:||||.|:.:.|......|.....::|.||.:||
Zfish   190 TTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWKGGETAVTGVSRIELPQFSIVD----- 249

  Fly   293 LTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGG 357
                 ||..                               :::|          .|.||
Zfish   250 -----YKLV-------------------------------SRNV----------VFSTG------ 262

  Fly   358 SGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATAD 422
                               .|..|.::|.|:|::|.|::|.|.|..|:.:|||||||:|.:|:|.
Zfish   263 -------------------AYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA 308

  Fly   423 RVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECY 487
            ||:||||||||||.:....|..|||:.|..|:|.::...|.|:|..:|::|.|:|.. :|.|
Zfish   309 RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIF-FGRG--- 369

  Fly   488 FIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRH 552
                                                       |....:|.....:....||:..
Zfish   370 -------------------------------------------PQMQKKLAEKAEKANNDRNKYD 391

  Fly   553 GLWSMKLLGLFDWRRRRKPPRADSDEDED--------DEQ-----TQLRA-NEAPTTSAAAAAAQ 603
            |..|::..|      ..||..........        |.|     |.|.. ||........:.::
Zfish   392 GNKSVQEGG------NCKPSSVKQSNQVQGHRHSRGVDSQGNILLTTLEIHNEVAGNEITTSVSE 450

  Fly   604 AAAQAARISPPTGGRRRMSYYRREEMEARRKGK-------------RTPQYNSVSKIDRASRIVF 655
            |....:.:...:|.:.|.....|..|:...:.|             :.|....|:.|||.|||:|
Zfish   451 ARNSTSMVFDNSGIQYRKQSTARHSMDRNAQSKKPRLRRRSSQLKIKIPDLTDVNAIDRWSRIIF 515

  Fly   656 PLLFILINVFYWYGYLS 672
            |.:|.|.|:.||..|::
Zfish   516 PAVFSLFNLIYWLYYVN 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	78/218 (36%)
		LIC	111..670	CDD:273305	166/585 (28%)
		Neur_chan_memb	398..667	CDD:280999	75/295 (25%)
gabrb3	XP_005166136.1	LIC	61..530	CDD:273305	169/597 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810