Protein Alignment Grd and LOC5667031

DIOPT Version :10

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_061505913.1
• Gene: LOC5667031 / 5667031
• VectorBaseID: AGAMI1_008409
• Length: 471
• Species: Anopheles gambiae
• Alignment Length: 570
• Identity: 111/570 - (19%)
• Similarity: 205/570 - (35%)
• Gaps: 148/570 - (25%)

  Fly   120 YDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRL--AFEG-AQDTLALS 181
            ||.:::|  .|....:.|.:.:..:..:.|.....|.|.:.:.:|.|.|:  .|.. ..:.:.|:
Mosquito    34 YDKNVKP--AGTLTDVSVSLYINRISGVDENKEEISFDVFLQITWEDLRIQPVFNNKVGEYVELT 96

  Fly   182 VSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMNLADFPMDIQK 246
            .:....||.||.|....::..:.|:......:|:|:|..:..|...||...|.|:...:|:|:|:
Mosquito    97 KADRDMIWVPDLYIRQLREMKMLTLFEEISSLRLYENSTISLSIGATIIIKCDMDFVLYPLDVQR 161

  Fly   247 CPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVYKAAAPRPQRRPFN 311
            ||:.|.|:.|...|:.:||..|. .::...|.....|.|
Mosquito   162 CPVDFSSYKYPVKDLRFRWRSEN-ALSFPNDFGDGFFRL-------------------------- 199

  Fly   312 NKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTGLSGTITLETNHPS 376
                    .|.:.:|                           .|.........|     :.||
Mosquito   200 --------PKYVVSF---------------------------YTEQESQIVNYS-----DDNH-- 222

  Fly   377 EYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEA 441
              |...:...|.|.:.::|::.|.|..|.|.:||.||.:..|....|:.|.:||:|::..:....
Mosquito   223 --SSARLEITLSREVKSYLLENYLPSTLFVSISWGSFVVVPEIVPGRMVLLVTTLLSLITMFDTV 285

  Fly   442 RTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEELDSESGESETEPLT 506
            |.:.|.......|:.::.....|:|..::::.:|.:..:|
Mosquito   286 RNNSPDALELKCLEVWLISCTLFVFFALMEYFIVLFGIRY------------------------- 325

  Fly   507 SDFRGSTESKIYEVIPLSMCAISMPPPPT--------RLGMLTSRNRRPRNRRHGL--WSMKLLG 561
                    .|.:.|.. :..|.|:||..|        :..|.||.|.....|.:||  .::|:.|
Mosquito   326 --------DKHWRVAK-AQHASSIPPSITLQSAVTMAQSTMDTSINSASFQRENGLEHATLKVSG 381

  Fly   562 LFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARISPPTGGRRRMSYYRR 626
                                ..:.|...:.:.||||:.:..|...|:|:.......|:|  :...
Mosquito   382 --------------------TNKIQPHDHNSKTTSASLSNIQDTVQSAQKVSSVMTRKR--FRNV 424

  Fly   627 EEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYLSRSSR 676
            .::.....|.:.      .::|:.|.|:||:.|::..:.||..||:.|.:
Mosquito   425 ADVALLYAGSQR------GRLDQLSLIIFPVSFLIFTISYWTMYLTESKK 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	LIC	111..670	CDD:455710	108/562 (19%)
		LGIC_ECD_GABAR_GRD-like	132..300	CDD:349808	38/170 (22%)
		Cys-loop	233..247	CDD:349808	5/13 (38%)
LOC5667031	XP_061505913.1	None