Protein Alignment Grd and gabrz

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001108214.2
• Gene: gabrz / 561738
• ZFINID: ZDB-GENE-080303-26
• Length: 447
• Species: Danio rerio
• Alignment Length: 572
• Identity: 157/572 - (27%)
• Similarity: 248/572 - (43%)
• Gaps: 158/572 - (27%)

  Fly   107 ANISELL----DNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDK 167
            ||..|:|    ..|::||:..:||.||..|.|:.:.:.:.|:..|||::|.|:...:.||.|.|:
Zfish    25 ANTEEILPPTIQKLMKGYNKYLRPFFGNGPVTVGMSLDIASIDTISEINMDYTATIFLRQRWTDE 89

  Fly   168 RLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAG 232
            ||.|:| ..:|:|...::..:|.|||:..:.|:|:||.||..|:.:||:.||.|||:.|:|....
Zfish    90 RLCFDG-NKSLSLDGRLVELLWVPDTFIVDSKKSFLHDITVENRLIRIFPNGTVLYALRITTTVA 153

  Fly   233 CPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIV 297
            |.|:|..:|||.|.|.|:..|:||...||::.|.:....|:..:.::|:|:.|.|
Zfish   154 CSMDLTKYPMDRQTCMLQLESWGYNVKDVVFYWTRGNQSVSGLDHLQLAQYTLED---------- 208

  Fly   298 YKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTT 362
                               ..||:                      .:..:.||
Zfish   209 -------------------HYTSE----------------------SEAVYETG----------- 221

  Fly   363 GLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLG 427
                      |:|.    |:.:|.|:|.:..|:::.|.|...||||||||||:::.:...|:.:|
Zfish   222 ----------NYPK----LIFHFKLKRSILYFILETYVPSSALVVLSWVSFWISQSSVPARICIG 272

  Fly   428 ITTVLTMTFLGLEARTDLPKVS-YPTALDFFVFLSFGFIFATILQFAVVHYYTKY--GSGECYFI 489
            :|||||||.|.:.|||.||..: :..|:|.::.:.|.|||..::::||.|:.|.:  .:...|..
Zfish   273 VTTVLTMTTLMMGARTSLPNANCFIKAIDVYLGICFSFIFGALIEYAVAHFCTLHQPNAANAYMY 337

  Fly   490 IEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGL 554
            .:|:  :..|.|...:.:.|                               .|...|.|.|...|
Zfish   338 GQEM--QEREDEMNGIVTSF-------------------------------GSHALRARKREEML 369

  Fly   555 WSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARISPPTGGRR 619
            ..|..:        ..|..::|.||....|.|.|            ..:..::|.||.
Zfish   370 SRMGSV--------NNPTPSESKEDVSSSQPQTR------------CTKCMSRARRII------- 407

  Fly   620 RMSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYL 671
            |..|..:.|         .|.|     ||..||:.|||.|::||:.||..||
Zfish   408 RCLYCCKVE---------NPHY-----IDNYSRLTFPLSFVIINLLYWTYYL 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	69/219 (32%)
		LIC	111..670	CDD:273305	153/565 (27%)
		Neur_chan_memb	398..667	CDD:280999	73/271 (27%)
gabrz	NP_001108214.2	LIC	26..444	CDD:273305	154/568 (27%)
		LGIC_ECD_GABAAR_pi	54..235	CDD:349805	67/257 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810