Protein Alignment Grd and gabra6b

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_002667403.3
• Gene: gabra6b / 559693
• ZFINID: ZDB-GENE-080815-1
• Length: 444
• Species: Danio rerio
• Alignment Length: 591
• Identity: 194/591 - (32%)
• Similarity: 263/591 - (44%)
• Gaps: 205/591 - (34%)

  Fly   108 NISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAFE 172
            ||:.:||.||.||||.:||.||||...::.||.|.|.||:|:|:|.|:||.:|||:|:|.||.||
Zfish    30 NITRILDRLLDGYDNRLRPGFGGPVTEVKTDIFVTSFGPVSDVEMEYTMDVFFRQTWIDDRLKFE 94

  Fly   173 GAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMNL 237
            |..:.|.|:..|:::||.|||:|.|||:|..|.:|||||..||.|||.:||:.||||.|.|||.|
Zfish    95 GPIEILRLNNLMVSKIWTPDTFFRNGKRSISHNMTTPNKLFRIMQNGTILYTMRLTINAECPMRL 159

  Fly   238 ADFPMDIQKCPLKFGSFGYTTSDVIYRWNK------ERPPVAIAEDMKLSQFDLVDCPAGNLTDI 296
            .:||||...|||||||:.|..|:::|.|.|      |.|    .|...|.|:||:
Zfish   160 INFPMDGHSCPLKFGSYAYPMSEIVYTWKKGPLFSVEVP----QESSSLLQYDLI---------- 210

  Fly   297 VYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGST 361
                                                .|.|....||                 |.
Zfish   211 ------------------------------------GQTVSSERLK-----------------SN 222

  Fly   362 TGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSL 426
            ||             ||.::.|.|||||.||.||||.|.||.:.|:|:.||||:::|:...|...
Zfish   223 TG-------------EYIVMTVYFHLQRKMGFFLIQTYIPCIMTVILAQVSFWIDKESVPARTVF 274

  Fly   427 GITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIE 491
            |||||||||.|.:.||..||||||.||:|:|:.:.|.|:|:.:::||.|:|:
Zfish   275 GITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF------------- 326

  Fly   492 ELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWS 556
                           |..:.:.|.:
Zfish   327 ---------------STLQANKELR---------------------------------------- 336

  Fly   557 MKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARISPP--TGG-- 617
                                           |||.|   .||||||.|.:....:..|  .||
Zfish   337 -------------------------------RANIA---RAAAAAAAARSDGEGVLNPLDPGGVL 367

  Fly   618 RRRMS----------YYRREEMEARRKGKRTPQYN---SVSKIDRASRIVFPLLFILINVFYWYG 669
            ::||:          :.|..:.:..::|...|..|   ..|.||:.|||:|||.|...|:.||..
Zfish   368 KKRMNSLSQRSATDRFSRPSQSDFHQQGSAVPANNMLIGTSIIDKYSRILFPLSFGAFNLVYWIV 432

  Fly   670 YLSRSS 675
            ||::.:
Zfish   433 YLTKDT 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	94/221 (43%)
		LIC	111..670	CDD:273305	190/581 (33%)
		Neur_chan_memb	398..667	CDD:280999	73/285 (26%)
gabra6b	XP_002667403.3	Neur_chan_LBD	32..239	CDD:280998	109/286 (38%)
		LIC	33..433	CDD:273305	190/581 (33%)
		Neur_chan_memb	246..430	CDD:280999	73/285 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	199	1.000	Domainoid score	I3005
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	368	1.000	Inparanoid score	I2100
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105663
Panther	1	1.100	-	-	O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X127
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.960