Protein Alignment Grd and glrbb

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_021336678.1
• Gene: glrbb / 445193
• ZFINID: ZDB-GENE-040801-106
• Length: 502
• Species: Danio rerio
• Alignment Length: 652
• Identity: 174/652 - (26%)
• Similarity: 268/652 - (41%)
• Gaps: 176/652 - (26%)

  Fly    43 ISCC----------LLMLCIYPNAWPWSIGPGSGPFSVSADSIKGRGDTHRLGEMGTSLSSSLPS 97
            :|||          ||::|:      |.    .|.|:....:.||:    :.|:. ....|.|.|
Zfish     4 LSCCNMKALKVIFMLLIICL------WM----EGGFTKEKSAKKGK----KKGKQ-VYCPSQLSS 53

  Fly    98 SWLTQ--SNNHANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYF 160
            ..|.:  :|:.:||   |:.||..||..|||:|.|.|....|:|.:.|.|.|.|..|.|.::.:.
Zfish    54 EDLARVPANSTSNI---LNKLLITYDPRIRPNFKGIPVEDRVNIFINSFGSIQETTMDYRVNIFL 115

  Fly   161 RQSWVDKRLAF--EGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLY 223
            ||.|.|.||..  :...|:|.:...|...:||||.:|.|.|.:..|.:|..|..:.|::||.||.
Zfish   116 RQRWNDPRLRLPQDFKSDSLTVDPKMFKCLWKPDLFFANEKSANFHDVTQENILLFIFRNGDVLI 180

  Fly   224 SSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDL--V 286
            |.||::...||::|..||||.|:|.::..||||||.|:.:.| :...||.: :::.|.|||:  .
Zfish   181 SMRLSVTLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLQFMW-QSGDPVQM-DEIALPQFDIKQE 243

  Fly   287 DCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTG 351
            |...||.|                                       ::..|||.
Zfish   244 DIEYGNCT---------------------------------------KYYAGTGY---------- 259

  Fly   352 RDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLN 416
                                      |:.:.|.|.|:|.:|.:::.||.|..|:|||||:|||:|
Zfish   260 --------------------------YTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWIN 298

  Fly   417 REATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKY 481
            .:|:|.||.|||.:||:::.......::||||||..|:|.::.....|.||:::::|||......
Zfish   299 PDASAARVPLGILSVLSLSSECTSLASELPKVSYVKAIDIWLIACLLFGFASLVEYAVVQVMLNS 363

  Fly   482 GSGECYFIIEE-----LDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRL-GML 540
            ..     ::|.     ...|..|.:| |..:...|...:.|:        ..::....||. .:.
Zfish   364 PK-----LLEAERAKIATKEKAEGKT-PAKNTINGMGSTPIH--------VSTLQVTETRCKKVC 414

  Fly   541 TSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAA 605
            ||::....|      ...::|..        ||       |.|.:.......|....:|.:...|
Zfish   415 TSKSDLRTN------DFSIVGSL--------PR-------DFELSNFDCYGKPIEVGSAFSKSQA 458

  Fly   606 AQAARISPPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSK-IDRASRIVFPLLFILINVFYWYG 669
            ....:..||                       .|...|.:| ||..:|.:||..|:..||.||..
Zfish   459 KNNKKPPPP-----------------------KPVIPSAAKRIDLYARALFPFSFLFFNVIYWSV 500

  Fly   670 YL 671
            ||
Zfish   501 YL 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	73/219 (33%)
		LIC	111..670	CDD:273305	153/569 (27%)
		Neur_chan_memb	398..667	CDD:280999	69/275 (25%)
glrbb	XP_021336678.1	Neur_chan_LBD	53..501	CDD:332142	158/585 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810