Protein Alignment Grd and pHCl-2

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 628
• Identity: 141/628 - (22%)
• Similarity: 228/628 - (36%)
• Gaps: 182/628 - (28%)

  Fly    68 FSVSADSIKGRGDTHRLGEMGTSLSSSLPSSWLTQSNNHANISELLDNLLR--GYDNSIRP---- 126
            ||||.:             :..|..::.||  |..:.:.| :.|||..|..  .||..:.|
  Fly    47 FSVSIN-------------LSQSTVNNCPS--LKNAESMA-LMELLTRLTAPCRYDRMVPPVVHN 95

  Fly   127 -DFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAFEG-----AQDTLALSVSML 185
             |....|..|.....:..|..:...|:.:::....:..::|.||||..     .|..:..| .:.
  Fly    96 KDGEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGES-ELK 159

  Fly   186 ARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLK 250
            ..:|.|..:..|.:.|.:...:..::...||.||.||.|:||.....|.||...||.|.|||...
  Fly   160 KMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTT 224

  Fly   251 FGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDP 315
            ..|:.|.|:.|...|..:. ||:..:.::|::::|:    |:|
  Fly   225 LESWMYNTTLVQLHWETDN-PVSFDKQLQLTEYNLI----GSL---------------------- 262

  Fly   316 PRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTGLSGTITLETNHPSEYSM 380
                            .|:.:|            ...::....||..|             .||:
  Fly   263 ----------------YNESIR------------VSNESYMSHGSLEG-------------NYSI 286

  Fly   381 LMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDL 445
            :.....|.|.:|.::|..:.|..::|.:|||||||..:.|..|.:||.||:|:...|.|....:|
  Fly   287 ISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNL 351

  Fly   446 PKVSYPTALDFFVFLSFGFIFATILQFAVVHYY-------------TKYGSGECYFIIEELDSES 497
            .||||.|..:.:..:...|||.::::||.|:..             |||.....:....:.....
  Fly   352 MKVSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRH 416

  Fly   498 GESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMKLLGL 562
            |...|:...|..  ||.|......| :...|::..|....|.|:
  Fly   417 GYRRTDSTMSTM--STTSMDKTCGP-NNTVITIETPIIIGGSLS--------------------- 457

  Fly   563 FDWRRRRKPPRADS--DEDEDDEQTQLRANEAPTTSAAAAAAQAAAQA-ARISPPTGGRRRMSYY 624
                      |.||  ..||.||.:        |:.::.::.:..||. |.::|     :.:|.:
  Fly   458 ----------REDSAISLDEQDETS--------TSESSDSSKEKPAQTFATMTP-----KEVSLW 499

  Fly   625 RREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYW 667
                                  |||..|.||||.||:.|..:|
  Fly   500 ----------------------IDRKMRFVFPLSFIVFNALFW 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	52/227 (23%)
		LIC	111..670	CDD:273305	132/585 (23%)
		Neur_chan_memb	398..667	CDD:280999	68/284 (24%)
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	141/628 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447285
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840