Protein Alignment Grd and GluClalpha

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Alignment Length: 611
• Identity: 172/611 - (28%)
• Similarity: 259/611 - (42%)
• Gaps: 196/611 - (32%)

  Fly    93 SSLPSSWLTQSNNHANIS------ELLDNLLRG--YDNSIRPD-FGGP--PATIEVDIMVRSMGP 146
            :||.|:.|.   |:|.|:      ::||.:|..  ||..|||. ..|.  ||.:.|:|.|||:..
  Fly    14 ASLCSASLA---NNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSISK 75

  Fly   147 ISEVDMTYSMDCYFRQSWVDKRLAFEGAQDTLA-LSVSMLARIWKPDTYFYNGKQSYLHTITTPN 210
            |.:|.|.||:...||:.|.|:||.|:..|..|. |:::...|:|.||.:|.|.|:.:.|.|..||
  Fly    76 IDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKYLTLTEANRVWMPDLFFSNEKEGHFHNIIMPN 140

  Fly   211 KFVRIYQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIA 275
            .::||:.||.||||.|:::...|||||..:|:|.|.|.|:..|:|:||:|:::.| ||..||.:.
  Fly   141 VYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLW-KEGDPVQVV 204

  Fly   276 EDMKLSQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTG 340
            :::.|.:|.|                                  .|.:|.:.
  Fly   205 KNLHLPRFTL----------------------------------EKFLTDYC------------- 222

  Fly   341 LKLDKGAFGTGRDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLL 405
                            .|.:.||             |||.|.|:...:|....:|||:|.|||:|
  Fly   223 ----------------NSKTNTG-------------EYSCLKVDLLFKREFSYYLIQIYIPCCML 258

  Fly   406 VVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATIL 470
            |::|||||||::.|...|||||:||:|||..........||.|||..|:|.:..:...|:|..:|
  Fly   259 VIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALL 323

  Fly   471 QFAVVHYYTKYGSGECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPT 535
            :||:|:|.::.||.:.
  Fly   324 EFALVNYASRSGSNKA------------------------------------------------- 339

  Fly   536 RLGMLTSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAA 600
                    |....|.:              ::||           |.||..|.|......:.:.|
  Fly   340 --------NMHKENMK--------------KKRR-----------DLEQASLDAASDLLDTDSNA 371

  Fly   601 AAQAAAQAARISPPTGGRRR---------MSYYRREEMEARRKGKRTP--------QYNSVSK-I 647
            ....|:|.||    .||:::         ::..:|.:.|...:..:.|        ::.:.|| |
  Fly   372 TFAMASQFAR----GGGQQKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRI 432

  Fly   648 DRASRIVFPLLFILINVFYWYGYLSR 673
            |..|||.|||:|.|.|:.||..||.|
  Fly   433 DVISRITFPLVFALFNLVYWSTYLFR 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	76/227 (33%)
		LIC	111..670	CDD:273305	162/582 (28%)
		Neur_chan_memb	398..667	CDD:280999	72/286 (25%)
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	169/606 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447364
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940