Protein Alignment Grd and gabra6a

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_005173169.1
• Gene: gabra6a / 393704
• ZFINID: ZDB-GENE-040426-1692
• Length: 435
• Species: Danio rerio
• Alignment Length: 591
• Identity: 184/591 - (31%)
• Similarity: 252/591 - (42%)
• Gaps: 200/591 - (33%)

  Fly   102 QSNNHANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVD 166
            |..|..||:.:||.||.||||.:||..|.....::.||.|.|.||:|:|:|.::||.:|||.|||
Zfish    20 QKINSENITRILDGLLEGYDNRLRPGSGVSVTEVKTDIFVTSFGPVSDVNMEFTMDMFFRQMWVD 84

  Fly   167 KRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKA 231
            :||||:|..:.|.|:..|:.:||.|||:|.|.::|..|.:|:|||..||.|||.|.|:.|||:.|
Zfish    85 ERLAFQGPIEILPLNNRMVDKIWTPDTFFRNARKSLAHNMTSPNKLFRIMQNGTVFYTMRLTVSA 149

  Fly   232 GCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNK------ERPPVAIAEDMKLSQFDLVDCPA 290
            .|||.|.|||||...|||.|||:.||..:::|.|.|      :.||    |...|.|:||:
Zfish   150 VCPMVLRDFPMDGHTCPLYFGSYAYTNREIVYTWRKGLEASVDFPP----ESSSLLQYDLL---- 206

  Fly   291 GNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDAT 355
                                                           |..|..:...|.||.
Zfish   207 -----------------------------------------------GQTLFTETYKFSTGL--- 221

  Fly   356 GGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREAT 420
                                  ||:.:|:|:|||.:|..|||.|.|..::||||.||||:|:|:.
Zfish   222 ----------------------YSVQVVHFYLQRKLGYHLIQTYIPLIMVVVLSQVSFWINKESV 264

  Fly   421 ADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGE 485
            ..|...|||||||||.|.:.||:.||||||.||:|:|:.:.|.|:.:.:::||.|:||....:.
Zfish   265 PARTVAGITTVLTMTTLSISARSSLPKVSYATAMDWFIAVCFAFVASALVEFAAVNYYATLEAN- 328

  Fly   486 CYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNR 550
                                                                             
Zfish   329 ----------------------------------------------------------------- 328

  Fly   551 RHGLWSMKLLGLFDWRRRRKPPRADSDEDE----DDEQTQLRANEAPTTSAAAAAAQAAAQAARI 611
                           |...|.||....|.:    |||.      |:|.:..:|.:
Zfish   329 ---------------RENHKLPRGSIVESQAQGSDDEP------ESPQSDTSAYS---------- 362

  Fly   612 SPPTGGRRRMSYYRREEMEAR----RKGKRTP---QYNSVSKIDRASRIVFPLLFILINVFYWYG 669
                  |:|..|...|....|    .:|...|   .....|.||:.|||:|||.|.:.|:.|||.
Zfish   363 ------RKRRGYPVSEAPRTRVPIFLQGSAFPPNMMLAGTSAIDKYSRILFPLAFGIFNLVYWYI 421

  Fly   670 YLSRSS 675
            |||:.:
Zfish   422 YLSKDT 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	87/221 (39%)
		LIC	111..670	CDD:273305	177/575 (31%)
		Neur_chan_memb	398..667	CDD:280999	71/279 (25%)
gabra6a	XP_005173169.1	LIC	2..422	CDD:273305	181/584 (31%)
		Neur_chan_LBD	28..234	CDD:280998	98/285 (34%)
		Neur_chan_memb	242..419	CDD:280999	71/279 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	199	1.000	Domainoid score	I3005
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	368	1.000	Inparanoid score	I2100
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X127
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.060