Protein Alignment Grd and gabrb2a

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001019558.2
• Gene: gabrb2a / 336252
• ZFINID: ZDB-GENE-030131-8196
• Length: 519
• Species: Danio rerio
• Alignment Length: 599
• Identity: 171/599 - (28%)
• Similarity: 267/599 - (44%)
• Gaps: 141/599 - (23%)

  Fly   104 NNHANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKR 168
            :|...:.:.:|.|::|||..:||||||.|..:.::|.:.|:..:|||:|.|::..||:|:|.|||
Zfish    30 SNMPVVKDTVDRLMKGYDIRLRPDFGGAPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKR 94

  Fly   169 LAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGC 233
            |::......|.|...:..::|.|||||.|.|:|::|.:|..|:.:|::.:|.|||..|:|..|.|
Zfish    95 LSYSEIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAAC 159

  Fly   234 PMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVY 298
            .|:|..:|:|.|.|.|:..|:||||.|:.:.|......|:..|.::|.||.:||          |
Zfish   160 MMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDGAVSGVERIELPQFSIVD----------Y 214

  Fly   299 KAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTG 363
            |.                             .:||.            .|.||
Zfish   215 KL-----------------------------ISKNV------------VFSTG------------ 226

  Fly   364 LSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGI 428
                         .|..|.::|.|:|::|.|::|.|.|..|:.:|||||||:|.:|:|.||:|||
Zfish   227 -------------SYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 278

  Fly   429 TTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEEL 493
            |||||||.:....|..|||:.|..|:|.::...|.|:|..:|::|.|:|.. :|.|      .:.
Zfish   279 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIF-FGRG------PQR 336

  Fly   494 DSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTR--LGMLTSRN-----RRPRNRR 551
            ..::.|..........|                     |.|.:  :|.:..|:     |..:...
Zfish   337 QKKAAEKAATANNEKLR---------------------PDPNKWLVGSVVQRDDALYARMKQREI 380

  Fly   552 HGLWSM--------KLLGLFDWRRRRKPP--------------RADSDEDEDDEQTQLRANEAPT 594
            .|..||        ..|||.|.|.:..|.              .:|......|.::.:.|.::.|
Zfish   381 DGYDSMWDPIFAEDAALGLGDQRLKMTPDDIRLTTVEMKNEMGPSDLSRGLGDPRSTMLAYDSST 445

  Fly   595 TS--AAAAAAQAAAQAARISPPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPL 657
            ..  .||.|.|....:|.....|..:.|:   ||...:.:   ...|..:.|:.||:.||::||.
Zfish   446 LQYRRAAMARQNYGHSALERHATQKKSRL---RRRASQLK---VNIPDLSDVNSIDKWSRMIFPT 504

  Fly   658 LFILINVFYWYGYL 671
            ||...|:.||..|:
Zfish   505 LFSFFNIVYWLYYV 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	73/215 (34%)
		LIC	111..670	CDD:273305	169/589 (29%)
		Neur_chan_memb	398..667	CDD:280999	81/299 (27%)
gabrb2a	NP_001019558.2	LIC	7..517	CDD:273305	170/596 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900