Protein Alignment Grd and Gabrr3

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001074659.1
• Gene: Gabrr3 / 328699
• MGIID: 3588203
• Length: 464
• Species: Mus musculus
• Alignment Length: 568
• Identity: 154/568 - (27%)
• Similarity: 242/568 - (42%)
• Gaps: 160/568 - (28%)

  Fly   106 HANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLA 170
            |....:||.  :..:|.|.||.|||.|..:.:|:.|.|:..||||:|.::|..|.|..|.|:||:
Mouse    55 HPKREQLLH--IEDHDFSTRPGFGGSPVPVGIDVQVESIDSISEVNMDFTMTFYLRHYWKDERLS 117

  Fly   171 FEGAQD-TLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCP 234
            |....: ::.....:|.:||.||.:|.:.|:|::|..|..|..:|::.:|.||:|.|:|:.|.|.
Mouse   118 FPSTTNKSMTFDRRLLQKIWVPDIFFVHSKRSFIHDTTVENIMLRVHPDGNVLFSLRITVSAMCF 182

  Fly   235 MNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVYK 299
            |:.:.||:|.|.|.|:..|:.|...|::..|......:...|.:.||||.:.:..|
Mouse   183 MDFSRFPLDTQNCSLELESYAYNEEDLMLYWKHGNKSLNTEERISLSQFFIEEFSA--------- 238

  Fly   300 AAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTGL 364
                                                  .:||     ||          .|:||.
Mouse   239 --------------------------------------SSGL-----AF----------YSSTGW 250

  Fly   365 SGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGIT 429
                         |..|.:||.|:||:..|::|.|.|..|:|:|||||||::|.|...|||||||
Mouse   251 -------------YYRLFINFVLRRHVFFFVLQTYFPAMLMVMLSWVSFWIDRRAVPARVSLGIT 302

  Fly   430 TVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEELD 494
            |||||:.:.......:|:|||..|:|.::::|..|:|.:::::|.|:|.|         .:||..
Mouse   303 TVLTMSTVVTGVSASMPQVSYVKAVDVYMWVSSLFVFLSVIEYATVNYLT---------TVEEWK 358

  Fly   495 SESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMKL 559
            ..:            |....|.:|.:                               ..:.:|..
Mouse   359 QLN------------RRGKISGMYHI-------------------------------DAVQAMAF 380

  Fly   560 LGLFDWRRRRKPPRADSDEDEDDEQTQLRANE-APTTSAAAAAAQAAAQAARISPPTGGRRRMSY 623
            .|.:.          ||:.|.|.....|.:.| :.:|....:....::|..|.|  .||
Mouse   381 DGCYH----------DSETDVDQTSFSLHSEEDSMSTKFTGSPCADSSQIKRKS--LGG------ 427

  Fly   624 YRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYL 671
                     ..|:...:.|.|  ||..||||||.::|:.|:|||..|:
Mouse   428 ---------NVGRIILENNHV--IDTYSRIVFPTVYIIFNLFYWGIYV 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	63/216 (29%)
		LIC	111..670	CDD:273305	152/560 (27%)
		Neur_chan_memb	398..667	CDD:280999	71/269 (26%)
Gabrr3	NP_001074659.1	LIC	58..463	CDD:273305	152/562 (27%)
		Neur_chan_LBD	59..264	CDD:280998	76/281 (27%)
		Neur_chan_memb	271..460	CDD:280999	71/269 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810