Protein Alignment Grd and nAChRalpha3

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001285015.1
• Gene: nAChRalpha3 / 31767
• FlyBaseID: FBgn0015519
• Length: 795
• Species: Drosophila melanogaster
• Alignment Length: 379
• Identity: 83/379 - (21%)
• Similarity: 142/379 - (37%)
• Gaps: 86/379 - (22%)

  Fly    98 SWLTQSNNHANISELLDNLLRGYDNSIRPDFGGPPA-TIEVDIMVRSMGPISEVDMTYSMDCYFR 161
            |:::.|..:.:...|.|:||..|:..:||......| |:.:.:.:..:..::..:...:.:.:..
  Fly    15 SFISSSTANPDAKRLYDDLLSNYNKLVRPVVNVTDALTVRIKLKLSQLIDVNLKNQIMTTNLWVE 79

  Fly   162 QSWVDKRLAFEGAQDTLALSVSML----ARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVL 222
            |||.|.:|.:|..:..   .|.||    ..||:||...||....... :|...|....| .|||.
  Fly    80 QSWYDYKLKWEPKEYG---GVEMLHVPSDHIWRPDIVLYNNADGNFE-VTLATKATLNY-TGRVE 139

  Fly   223 YSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAE-DMKLSQFDLV 286
            :......|:.|.:::..||.|.|.|.:||||:.|....|..|...|.....:.| .:.||:|
  Fly   140 WRPPAIYKSSCEIDVEYFPFDEQTCVMKFGSWTYDGFQVDLRHIDELNGTNVVEVGVDLSEF--- 201

  Fly   287 DCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTG 351
                       |                    ||........||.:|:            .|.|.
  Fly   202 -----------Y--------------------TSVEWDILEVPAVRNE------------KFYTC 223

  Fly   352 RDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLN 416
            .|                      ..|..:..|..::|....:.:.:..||..:..|:.:.|:|.
  Fly   224 CD----------------------EPYLDITFNITMRRKTLFYTVNLIIPCMGISFLTILVFYLP 266

  Fly   417 REATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATIL 470
            .: :.::|||.|:.:|::|...|.....:|    ||:|  .|.|...|:..|::
  Fly   267 SD-SGEKVSLSISILLSLTVFFLLLAEIIP----PTSL--VVPLLGKFVLFTMI 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	52/221 (24%)
		LIC	111..670	CDD:273305	81/366 (22%)
		Neur_chan_memb	398..667	CDD:280999	20/73 (27%)
nAChRalpha3	NP_001285015.1	Neur_chan_LBD	26..241	CDD:280998	61/287 (21%)
		Neur_chan_memb	248..>359	CDD:280999	20/73 (27%)
		Neur_chan_memb	<683..760	CDD:280999

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447334
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030