Protein Alignment Grd and Glra1

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_006246440.1
• Gene: Glra1 / 25674
• RGDID: 2704
• Length: 457
• Species: Rattus norvegicus
• Alignment Length: 608
• Identity: 180/608 - (29%)
• Similarity: 257/608 - (42%)
• Gaps: 207/608 - (34%)

  Fly    90 SLSSSLPSSWLTQSNNHANISELLDNLL---RGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVD 151
            ||::|..:.....:....:.|:.||.|:   .|||..|||:|.|||..:..:|.:.|.|.|:|..
  Rat    19 SLAASKEADAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETT 83

  Fly   152 MTYSMDCYFRQSWVDKRLAF-EGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRI 215
            |.|.::.:.||.|.|.|||: |...|:|.|..|||..|||||.:|.|.|.::.|.|||.||.:||
  Rat    84 MDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRI 148

  Fly   216 YQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKL 280
            .:||.||||.|:|:...|||:|.:||||:|.|.::..|||||.:|:|:.| :|:..|.:|:.:.|
  Rat   149 SRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEW-QEQGAVQVADGLTL 212

  Fly   281 SQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDK 345
            .||.|.:                        .||                          |:...
  Rat   213 PQFILKE------------------------EKD--------------------------LRYCT 227

  Fly   346 GAFGTGRDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSW 410
            ..:.||:                         ::.:...|||:|.||.:|||:|.|..|:|:|||
  Rat   228 KHYNTGK-------------------------FTCIEARFHLERQMGYYLIQMYIPSLLIVILSW 267

  Fly   411 VSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVV 475
            :|||:|.:|...||.||||||||||.....:|..||||||..|:|.::.:...|:|:.:|::|.|
  Rat   268 ISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAV 332

  Fly   476 HYYTKYGSGECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGML 540
            ::.::                   ...|.|.  ||
  Rat   333 NFVSR-------------------QHKELLR--FR------------------------------ 346

  Fly   541 TSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLR----------------- 588
                   |.|||  ....:|.||                :|||..:.|
  Rat   347 -------RKRRH--HKSPMLNLF----------------QDDEGGEGRFNFSAYGMGPACLQAKD 386

  Fly   589 ------ANEAPTTSAAAAAAQAAAQAARISPPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSKI 647
                  ||...||:.|.|.::        ||             |||       |........||
  Rat   387 GISVKGANNNNTTNPAPAPSK--------SP-------------EEM-------RKLFIQRAKKI 423

  Fly   648 DRASRIVFPLLFILINVFYWYGY 670
            |:.|||.||:.|::.|:|||..|
  Rat   424 DKISRIGFPMAFLIFNMFYWIIY 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	86/219 (39%)
		LIC	111..670	CDD:273305	175/585 (30%)
		Neur_chan_memb	398..667	CDD:280999	76/291 (26%)
Glra1	XP_006246440.1	LIC	7..446	CDD:273305	179/606 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810