Protein Alignment Grd and Gabrb2

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_008765857.1
• Gene: Gabrb2 / 25451
• RGDID: 2650
• Length: 506
• Species: Rattus norvegicus
• Alignment Length: 596
• Identity: 172/596 - (28%)
• Similarity: 264/596 - (44%)
• Gaps: 147/596 - (24%)

  Fly   104 NNHANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKR 168
            :|.:.:.|.:|.||:|||..:||||||||..:.::|.:.|:..:|||:|.|::..||:|:|.|||
  Rat    31 SNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKR 95

  Fly   169 LAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGC 233
            |::......|.|...:..::|.|||||.|.|:|::|.:|..|:.:|::.:|.|||..|:|..|.|
  Rat    96 LSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAAC 160

  Fly   234 PMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVY 298
            .|:|..:|:|.|.|.|:..|:||||.|:.:.|..:...|.....::|.||.:||          |
  Rat   161 MMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVD----------Y 215

  Fly   299 KAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTG 363
            |..                 |.||:                        |.||
  Rat   216 KLI-----------------TKKVV------------------------FSTG------------ 227

  Fly   364 LSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGI 428
                         .|..|.::|.|:|::|.|::|.|.|..|:.:|||||||:|.:|:|.||:|||
  Rat   228 -------------SYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 279

  Fly   429 TTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEEL 493
            |||||||.:....|..|||:.|..|:|.::...|.|:|..:|::|:|:|.. :|.|      .:.
  Rat   280 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIF-FGRG------PQR 337

  Fly   494 DSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMK 558
            ..::.|..........|.......|:.|                       ::.|.:...||.
  Rat   338 QKKAAEKAANANNEKMRLDVNKIFYKDI-----------------------KQNRTQYQSLWD-- 377

  Fly   559 LLGLFDWRRRRKPPRADS---------DEDEDDEQTQLR-ANEAPTTSAAAA-----AAQAAAQA 608
                        |.|..:         |..|:...:.|. .||..|:.|...     :...|..|
  Rat   378 ------------PTRWTTYYHFSLYMMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDA 430

  Fly   609 ARISPPTGGRRRMSYYRR--EEMEARRKGK----------RTPQYNSVSKIDRASRIVFPLLFIL 661
            :.|.....|..|.|:.|.  |...|::|.:          ..|....|:.|||.|||.||::|..
  Rat   431 SSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSF 495

  Fly   662 INVFYWYGYLS 672
            .|:.||..|::
  Rat   496 FNIVYWLYYVN 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	78/215 (36%)
		LIC	111..670	CDD:273305	170/585 (29%)
		Neur_chan_memb	398..667	CDD:280999	79/295 (27%)
Gabrb2	XP_008765857.1	LIC	9..504	CDD:273305	171/592 (29%)
		Neur_chan_LBD	40..242	CDD:280998	85/277 (31%)
		Neur_chan_memb	249..501	CDD:280999	79/295 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810