Protein Alignment Grd and glra4b

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001189440.1
• Gene: glra4b / 192125
• ZFINID: ZDB-GENE-020402-2
• Length: 492
• Species: Danio rerio
• Alignment Length: 584
• Identity: 191/584 - (32%)
• Similarity: 269/584 - (46%)
• Gaps: 157/584 - (26%)

  Fly   110 SELLDNLL---RGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAF 171
            |:.||.|:   .|||..|||:|.|||..:..:|.:.|.|.|:|..|.|.::.:.||.|.|.|||:
Zfish    44 SDFLDKLMGKTSGYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAY 108

  Fly   172 -EGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPM 235
             |...|:|.|..|||..|||||.:|.|.|.:..|.:||.||.:||:|||.||||.|||:...|||
Zfish   109 KEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPM 173

  Fly   236 NLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVYKA 300
            :|.:||||.|.|.::..|||||.:|:|::|..| .||.:|:|:.|.||.|.:
Zfish   174 DLKNFPMDTQTCTMQLESFGYTMNDLIFQWLDE-GPVQVADDLMLPQFVLKE------------- 224

  Fly   301 AAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTGLS 365
                       .||            .|...|:              :.||:
Zfish   225 -----------EKD------------LGYCTKH--------------YNTGK------------- 239

  Fly   366 GTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITT 430
                        ::.:.|.|||:|.||.:|||:|.|..|.|:|||||||:|.:|...||.|||||
Zfish   240 ------------FTCIEVKFHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITT 292

  Fly   431 VLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEELDS 495
            |||||.....:|..||||||..|:|.::.:...|:||.:|::|.|::.::... |.:.:..:|..
Zfish   293 VLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQYK-EFFRLRRKLRQ 356

  Fly   496 E---------SGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRR 551
            |         :|.:||:..:::..|.|.|:..: ...|.||        |...|.|:|:......
Zfish   357 EQRNRAASGQAGAAETKNKSNNVTGGTPSRNAQ-RQCSACA--------REEQLASQNQDLYFPG 412

  Fly   552 HGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARISPPTG 616
            .|:                             .|.| :.:.|.:.|||..|..        ||
Zfish   413 FGI-----------------------------DTSL-SGDGPLSEAAAMFAGL--------PP-- 437

  Fly   617 GRRRMSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYLSRSSRILAN 680
            |.......||...:|:|             ||..||.||||.|::.|||||..|     ::|.|
Zfish   438 GHALFDIRRRFVEQAKR-------------IDTISRAVFPLSFLVFNVFYWVTY-----KVLRN 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	89/219 (41%)
		LIC	111..670	CDD:273305	187/571 (33%)
		Neur_chan_memb	398..667	CDD:280999	83/277 (30%)
glra4b	NP_001189440.1	LIC	5..478	CDD:273305	188/572 (33%)
		Neur_chan_LBD	47..253	CDD:280998	97/281 (35%)
		Neur_chan_memb	260..475	CDD:280999	83/277 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810