Protein Alignment Grd and lgc-52

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_502839.3
• Gene: lgc-52 / 190669
• WormBaseID: WBGene00013517
• Length: 423
• Species: Caenorhabditis elegans
• Alignment Length: 572
• Identity: 121/572 - (21%)
• Similarity: 211/572 - (36%)
• Gaps: 201/572 - (35%)

  Fly   107 ANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAF 171
            |..::|...|:..|..:..|:  ..|..:||:|.::.:..||.:..|:::|.:....|.||||||
 Worm    43 AKATDLARILMTNYSRNALPE--PAPVKVEVEITIQDISDISAITGTFTIDYWISAIWNDKRLAF 105

  Fly   172 ---EGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGC 233
               :..:..|:|...|..::|.|:....|.|.:.:|....||..:.|:.||.:..:.|:..:|.|
 Worm   106 SHLDPCRKNLSLDHDMEPKLWSPNVCIVNSKSTKVHDSPKPNILLMIFPNGTIWLNYRIRSEAPC 170

  Fly   234 PMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVY 298
            .|||.:||:|..:|.|.|.|:.|..:||..:|.:..|...:..|..|..|.:.:...|::|:
 Worm   171 QMNLRNFPLDSIRCSLVFESYSYNAADVELQWLEWSPVSTVRNDYNLPDFRMTNITYGSVTE--- 232

  Fly   299 KAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTG 363
                                                                        ..|.|
 Worm   233 ------------------------------------------------------------AYTAG 237

  Fly   364 LSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGI 428
            :             :..|.|:.|.:|..|.:::|:|.|..:.|.:||::||::.:|...|::|.:
 Worm   238 M-------------WHRLSVSIHFERLYGFYILQMYLPTYISVFISWIAFWMDTKALPARITLSV 289

  Fly   429 TTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEEL 493
            ::::.:||........|||.||..|:|.::|...||||.::::.|:|.|..|
 Worm   290 SSLMALTFQFGNIVKSLPKASYVKAIDIWMFSCVGFIFFSLIELAIVAYNDK------------- 341

  Fly   494 DSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMK 558
                              ..:.::.||    .|::         |.|.|..
 Worm   342 ------------------MHDQRLREV----RCSV---------GNLNSNG-------------- 361

  Fly   559 LLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARISPPTGGRRRMSY 623
             :|.::...||                                                    |:
 Worm   362 -IGQYNSTTRR----------------------------------------------------SF 373

  Fly   624 YRREEMEARR-KGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYLSRS 674
            .   |:.||| ||....     :.|||.:.::||.:|.|.|:.||..||:.|
 Worm   374 V---ELSARRAKGSELG-----ASIDRVASMLFPTMFALFNLVYWAYYLTTS 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	55/218 (25%)
		LIC	111..670	CDD:273305	117/562 (21%)
		Neur_chan_memb	398..667	CDD:280999	52/269 (19%)
lgc-52	NP_502839.3	Neur_chan_LBD	45..248	CDD:280998	59/280 (21%)
		LIC	52..413	CDD:273305	116/557 (21%)
		Neur_chan_memb	259..>338	CDD:280999	26/78 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166535
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740