Protein Alignment Grd and lgc-42

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_497489.3
• Gene: lgc-42 / 189722
• WormBaseID: WBGene00021437
• Length: 412
• Species: Caenorhabditis elegans
• Alignment Length: 556
• Identity: 135/556 - (24%)
• Similarity: 202/556 - (36%)
• Gaps: 192/556 - (34%)

  Fly   126 PDFGGPPATIEV--DIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAFEGAQDTLALSVSMLARI 188
            |..|.|.|.::|  ...|.|:|.....:|||.||.|...||.|..:.....:..|.....:|.:|
 Worm    32 PRNGNPKAPLQVHFGFYVESLGNFRATEMTYDMDMYLYMSWQDDSMRHNETEHVLVNDKDILDKI 96

  Fly   189 WKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGS 253
            |.||.||.|.:.:|.|.:|..|..:.|...|.:.|.:|:|:...|.::|.|:|:|.|.|.:|..|
 Worm    97 WLPDLYFANARTAYFHKVTVHNFNMFISPQGTISYGTRVTLNLACNLDLKDYPLDYQTCYIKVIS 161

  Fly   254 FGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRP 318
            :.:..:::...| ....|:....::.|.:|
 Worm   162 YAHVKNEMNVSW-FPNDPIRFNPEIDLPEF----------------------------------- 190

  Fly   319 TSKVMTTFAGPAAKNQHVRGTGLKLDK----GAFGTGRDATGGSGSTTGLSGTITLETNHPSEYS 379
                            |:|.    |||    |.|                ..|:|..::...|:|
 Worm   191 ----------------HIRA----LDKDYCNGVF----------------LYTLTHNSSRVGEFS 219

  Fly   380 MLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTD 444
            .|:....|:|.:|..|:|.|.|..|:|.:||||||::|.|...||||..||:||::..|...|..
 Worm   220 CLLGMLKLKRAIGFHLVQSYIPTGLIVAISWVSFWIDRRAVPARVSLSFTTLLTLSTQGNGIRYA 284

  Fly   445 LPKVSYPTALDFFVFLSFGFIFATILQFAVVHYY----TKYGSGECYFIIEELDSESGESETEPL 505
            ||.|||..|:|:|..:...|||..:|:||.|:.|    .||.     .:.|::.|..|
 Worm   285 LPAVSYAKAIDYFYGVCMLFIFGVLLEFAAVNSYMRRANKYN-----HMAEKIQSAYG------- 337

  Fly   506 TSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMKLLGLFDWRRRRK 570
                                                                           .|
 Worm   338 ---------------------------------------------------------------GK 339

  Fly   571 PPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARISPPTGGRRRMSYYRREEMEARRKG 635
            |..||.|.|.::..|:...|      ....:|....:|.:.|     |:.:|
 Worm   340 PIIADYDSDYEEGPTKYYGN------LNKNSAHLMYKALKFS-----RKALS------------- 380

  Fly   636 KRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYL 671
                       ||:|:|..||.:|.:.|||||..||
 Worm   381 -----------IDKAARFAFPCVFAIFNVFYWLYYL 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	48/201 (24%)
		LIC	111..670	CDD:273305	133/553 (24%)
		Neur_chan_memb	398..667	CDD:280999	66/272 (24%)
lgc-42	NP_497489.3	Neur_chan_LBD	36..192	CDD:280998	46/207 (22%)
		Neur_chan_memb	239..401	CDD:280999	66/271 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810