Protein Alignment Grd and acc-3

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_508810.2
• Gene: acc-3 / 186307
• WormBaseID: WBGene00018880
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 580
• Identity: 135/580 - (23%)
• Similarity: 222/580 - (38%)
• Gaps: 153/580 - (26%)

  Fly   112 LLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAFE---G 173
            :::.||..|.:...|...|  ..:.:::.|:.:..::|:...:.||.|..:.|:|..|.:|   .
 Worm    69 IIEKLLNNYKSFRTPSESG--VIVWIEVWVQEVNSVNEITSDFDMDIYVTELWMDSALRYEHLNP 131

  Fly   174 AQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMNLA 238
            .:..|:|:..:|.:||||:|.|.|.|.:.:|.....|.|:.||.||.|..:.|:.:|..|.|:.:
 Worm   132 CKYNLSLNSEILDQIWKPNTVFINSKSANIHKSPFKNVFLMIYPNGTVWVNYRVQVKGPCSMDFS 196

  Fly   239 DFPMDIQKCPLKFGSFGYTTSDVIYRW-NKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVYKAAA 302
            .||||.|.|.|...||.|...:|..:| |...|...:.:::.|..|
 Worm   197 AFPMDQQSCHLTLESFSYNNQEVDMQWMNWTTPLSLLKKEIVLPDF------------------- 242

  Fly   303 PRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTGLSGT 367
                               ||:.::           |.||.:....|.
 Worm   243 -------------------VMSNYS-----------TSLKHEIYPAGV----------------- 260

  Fly   368 ITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTVL 432
                      ::.|.:.|...|..|.::.|.|.|..|.:.:||:||.|..:....|..||:.::|
 Worm   261 ----------WNELTMTFVFSRRYGWYIFQAYIPTYLTIFISWISFCLGPKMIPARTMLGVNSLL 315

  Fly   433 TMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEELDSES 497
            .:||.......:||:|||..|||.::.:...|:|.::|:.|::        |......|...::.
 Worm   316 ALTFQFGNIMRNLPRVSYVKALDVWMLVCLTFVFCSLLELAII--------GSMGARSENRQAQQ 372

  Fly   498 GESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMKLLGL 562
            .:.:.|..|...:|...|....::..|.|     |...|:    .||..|.:...   |.|..|.
 Worm   373 QKQQDEEATKHQKGRENSTCSHLMSPSSC-----PNSPRI----CRNHIPNDVPQ---SFKSYGS 425

  Fly   563 FDWRRRRK-----------PPRADSDED----EDDEQTQLRANEAPTTSAAAAAAQAAAQAARIS 612
            .|.|.|::           .|.|:..|.    :..|:||....|...:|.|:.
 Worm   426 TDPRMRKRLIIASSSTISHAPNANRSEKVLLLDGLEETQFSQVETKFSSMASI------------ 478

  Fly   613 PPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYLS 672
                  :...::..||                  |||.|.|:||.||.|.|:.||..||:
 Worm   479 ------KMKKHWTTEE------------------IDRLSMIMFPGLFTLFNIIYWTYYLT 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	55/217 (25%)
		LIC	111..670	CDD:273305	133/576 (23%)
		Neur_chan_memb	398..667	CDD:280999	67/283 (24%)
acc-3	NP_508810.2	Neur_chan_LBD	69..512	CDD:332142	133/576 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810