Protein Alignment Grd and acc-2

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_501567.1
• Gene: acc-2 / 183758
• WormBaseID: WBGene00008280
• Length: 445
• Species: Caenorhabditis elegans
• Alignment Length: 596
• Identity: 128/596 - (21%)
• Similarity: 216/596 - (36%)
• Gaps: 193/596 - (32%)

  Fly    90 SLSSSLPSSWLTQSNNHANISELLDNLLR--GYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDM 152
            |.||.:......:.:|....::::|.||.  ||:....|...|  .|:.|:|.::::..|.|:..
 Worm    31 SSSSYIHHKTNKKPDNCTRDTDIIDRLLNGTGYNKFRIPQEEG--MTVVVEIWIQAITSIDELTN 93

  Fly   153 TYSMDCYFRQSWVDKRLAFE---GAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVR 214
            .:.||.|..::|:|..|.|:   ..:..|:|:..:|.|:|.|::.|.|.|.:.:|.....:.|:.
 Worm    94 DFDMDIYITETWLDPALNFQTMTPCKGNLSLNHQVLDRLWTPNSCFINSKVAQIHNSPFRSVFLM 158

  Fly   215 IYQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMK 279
            ::.||.|:.:.|:.:|..|.::|::||:|:|||.|.:.||.|...:|..||:....||.....:.
 Worm   159 LFPNGTVMVNYRVRVKGPCSLDLSNFPLDLQKCSLIYESFNYNRQEVEMRWSDAEHPVFNLSKIM 223

  Fly   280 LSQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLD 344
            |..|||.:.               :.:||     ..|.|
 Worm   224 LPDFDLFEI---------------QTERR-----QEPYP-------------------------- 242

  Fly   345 KGAFGTGRDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLS 409
                         :|....|..||..|                 |....:.:|.|.|..|.:.:|
 Worm   243 -------------AGMWDELHVTIIFE-----------------RRFIWYFMQAYLPTYLTIFIS 277

  Fly   410 WVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAV 474
            |:||.|...|...|..||:.::|.:.|.......:||:|||...:|.::.:|..|||.::|:.|:
 Worm   278 WISFSLGSRAIPARTMLGVNSLLAIVFSFGNIMRNLPRVSYIKGIDVWMLVSMTFIFCSLLELAI 342

  Fly   475 VHYYTKYGSGECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGM 539
            |.:..:                   .||                         ::......::..
 Worm   343 VGFMVR-------------------DET-------------------------VAKKKQQKKISG 363

  Fly   540 LTSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQA 604
            ..||...|    ||:.|.        ||...||                              ..
 Worm   364 NISREESP----HGIISE--------RRFMFPP------------------------------GC 386

  Fly   605 AAQAARISPPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYG 669
            :..:..:|..|.|                   .||:     :||..|.::||..|.:.|:.||:.
 Worm   387 SESSKSLSSCTSG-------------------WTPE-----RIDSISSVMFPFSFFVFNIIYWFY 427

  Fly   670 YLSRSSRILAN 680
            |:.|...|..|
 Worm   428 YIHRKEIIKQN 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	60/220 (27%)
		LIC	111..670	CDD:273305	120/563 (21%)
		Neur_chan_memb	398..667	CDD:280999	51/268 (19%)
acc-2	NP_501567.1	Neur_chan_LBD	51..258	CDD:308532	65/284 (23%)
		Neur_chan_memb	267..>347	CDD:308533	27/79 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810