Protein Alignment Grd and lgc-48

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_506308.3
• Gene: lgc-48 / 183638
• WormBaseID: WBGene00008223
• Length: 366
• Species: Caenorhabditis elegans
• Alignment Length: 392
• Identity: 99/392 - (25%)
• Similarity: 171/392 - (43%)
• Gaps: 84/392 - (21%)

  Fly   108 NISELLDNLLR--GYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLA 170
            |.::|::.||:  ||.....|...|  .|:.|:..::.:..|||:...:.::.:..:.|.|..|.
 Worm    27 NEAQLMEKLLKGSGYSKHKIPRENG--ITVSVEFWIQEINSISEMTNDFELELFINEMWTDPSLR 89

  Fly   171 FE--GA-QDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAG 232
            |.  || :..|.|....|.::|.|:|.|.|.|.:.::..:..|.|:.::.||.|..:.|:.:|..
 Worm    90 FPHLGACKANLTLDQQTLTKLWTPNTCFVNSKFAEIYESSFQNVFLTLFDNGTVWVNYRVRVKGA 154

  Fly   233 CPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIV 297
            |.|:|.|||||.|.|.|.:.||.|...:|..:||.:|.||...::::::.|.|.|     :|..|
 Worm   155 CNMDLVDFPMDTQSCRLNYQSFTYNNEEVRLQWNSQRSPVFALQEIRIADFWLKD-----ITPAV 214

  Fly   298 YKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTT 362
            .|             :|.|                                             .
 Worm   215 IK-------------RDYP---------------------------------------------A 221

  Fly   363 GLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLG 427
            ||             :..|:|.|..:|....:.:|.|.|....:.:||::|.|..:|...|..:|
 Worm   222 GL-------------WDELVVTFVFERRYMWYFLQAYLPTFFSIFISWIAFSLGPQAITPRTMIG 273

  Fly   428 ITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEE 492
            :..:|:|.|.......:||:|||..|:|.::..|..|:|.::::.|:|.|..:. ..|...:||:
 Worm   274 VNALLSMIFHFGSIMKNLPRVSYIKAIDVWMLSSMTFVFLSLIELAIVGYKLQI-QREKEHVIEK 337

  Fly   493 LD 494
            :|
 Worm   338 VD 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	62/220 (28%)
		LIC	111..670	CDD:273305	98/389 (25%)
		Neur_chan_memb	398..667	CDD:280999	29/97 (30%)
lgc-48	NP_506308.3	Neur_chan_LBD	28..237	CDD:280998	68/286 (24%)
		Neur_chan_memb	245..>323	CDD:280999	24/77 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810