Protein Alignment Grd and lgc-47

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_741878.1
• Gene: lgc-47 / 181193
• WormBaseID: WBGene00009799
• Length: 428
• Species: Caenorhabditis elegans
• Alignment Length: 576
• Identity: 120/576 - (20%)
• Similarity: 207/576 - (35%)
• Gaps: 215/576 - (37%)

  Fly   107 ANISELLDNLLRGYDNSI---RPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKR 168
            ||.:|::|:||  .|.::   :.....|...:.:::.|:.:..:||:...:.:|.|..:.|.|..
 Worm    55 ANDTEIIDHLL--IDRALYYNKHKLPSPQVDVRIEMWVQEVTSVSELTQDFEIDLYMNEYWTDPG 117

  Fly   169 LAFE---GAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIK 230
            ||::   ..|..|:...:::..||.|:|.|.|.|::.||:....|.|:.::.||.|..:.|:...
 Worm   118 LAYDILNPCQGNLSFDWAVMQNIWTPNTCFINSKKAQLHSSPFTNVFLMVFPNGSVWSNWRIKST 182

  Fly   231 AGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTD 295
            ..|.|:|..||||..:|.|.|.||.|...:|..||..  ||:.|.:.::|..|
 Worm   183 GPCVMDLTKFPMDSIECTLTFESFNYNKDEVFMRWGD--PPLTIFKPIELPDF------------ 233

  Fly   296 IVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGS 360
                                      .||.|:           |..|....|.|
 Worm   234 --------------------------TMTNFS-----------TSNKFQLYAAG----------- 250

  Fly   361 TTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVS 425
                            .:|.|.|||..:|..|.:|:|.|.|..:.|.:||:.|:|..:|...|..
 Worm   251 ----------------YWSELNVNFLFRRRSGWYLLQGYIPTYMTVFISWIPFYLGPKAIPARTM 299

  Fly   426 LGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFII 490
            :|:..:|.:||.......:||:|||..|:|.::.....|:||::.:.|.:.:..:
 Worm   300 IGVNALLALTFQFGNIIRNLPRVSYIKAIDVWMLSGICFVFASLFELATIGFLMR---------- 354

  Fly   491 EELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLW 555
                     :|.:|.|.                                 :||:.:..||
 Worm   355 ---------NEGKPATK---------------------------------SSRSTKNSNR----- 372

  Fly   556 SMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARISPPTGGRRR 620
                     |::                         |:..
 Worm   373 ---------WQQ-------------------------PSVC------------------------ 379

  Fly   621 MSYYRREEMEARRKGKRTPQYNSV--SKIDRASRIVFPLLFILINVFYWYGYLSRS 674
                 ||  :.:||.:     |.|  .::|..||::||::|...|..||:.|:.::
 Worm   380 -----RE--DTQRKSQ-----NIVFCERLDNTSRLMFPVVFTFYNFIYWFVYMKQA 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	55/221 (25%)
		LIC	111..670	CDD:273305	117/566 (21%)
		Neur_chan_memb	398..667	CDD:280999	46/270 (17%)
lgc-47	NP_741878.1	Neur_chan_LBD	58..264	CDD:280998	65/285 (23%)
		LIC	59..419	CDD:273305	117/566 (21%)
		Neur_chan_memb	273..>352	CDD:280999	24/78 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910