Protein Alignment Grd and Gabrg1

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_034382.2
• Gene: Gabrg1 / 14405
• MGIID: 103156
• Length: 465
• Species: Mus musculus
• Alignment Length: 583
• Identity: 183/583 - (31%)
• Similarity: 263/583 - (45%)
• Gaps: 172/583 - (29%)

  Fly    94 SLPSSWLTQSNNH-ANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMD 157
            ::..:|:.....| .:|:::|::||:||||.:|||.|..|..||.|:.|.|:||:..::|.|::|
Mouse    48 TMNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTID 112

  Fly   158 CYFRQSWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVL 222
            ..|.|:|.|.||.|......|.|:.:|:.:||.|||:|.|.::|..|.|||||:.:||:.:||||
Mouse   113 IIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVL 177

  Fly   223 YSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVD 287
            |:.||||.|.|.:.|.:||||...|||:|.|:||..:::.|:|.|....||..:..:|.||..|
Mouse   178 YTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFV- 241

  Fly   288 CPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGR 352
                                                                ||:
Mouse   242 ----------------------------------------------------GLR---------- 244

  Fly   353 DATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNR 417
                   ::|.:|.||:      .:|.::.:.|.|.|.||.|.||.|.||.|.|||||||||:|:
Mouse   245 -------NSTEISHTIS------GDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINK 296

  Fly   418 EATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYG 482
            :|...|.|||||||||||.|...||..||||||.||:|.||.:.|.|:||.::::..:||:|...
Mouse   297 DAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNN 361

  Fly   483 SGECYFIIEELDSESG---ESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRN 544
            .|:         :..|   :::|........|||      :||::  :||:|
Mouse   362 KGK---------TTRGRKLKNKTSASPGLHAGST------LIPMN--SISLP------------- 396

  Fly   545 RRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQ-LRANEAPTTSAAAAAAQAAAQA 608
                                             :.|||...| |...:.  ||........
Mouse   397 ---------------------------------QGEDDYGYQCLEGKDC--TSFFCCFDDC---- 422

  Fly   609 ARISPPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYL 671
                       |...:|...:..|           ::|||..|||.||..|.|.|:.||.|||
Mouse   423 -----------RTGSWREGRIHIR-----------IAKIDSYSRIFFPTAFALFNLVYWVGYL 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	80/215 (37%)
		LIC	111..670	CDD:273305	177/562 (31%)
		Neur_chan_memb	398..667	CDD:280999	80/272 (29%)
Gabrg1	NP_034382.2	Neur_chan_LBD	65..270	CDD:280998	90/280 (32%)
		LIC	66..462	CDD:273305	177/562 (31%)
		Neur_chan_memb	277..459	CDD:280999	80/272 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	199	1.000	Domainoid score	I3055
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X127
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.000