Protein Alignment Grd and Gabre

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_059065.2
• Gene: Gabre / 14404
• MGIID: 1330235
• Length: 916
• Species: Mus musculus
• Alignment Length: 606
• Identity: 158/606 - (26%)
• Similarity: 252/606 - (41%)
• Gaps: 184/606 - (30%)

  Fly    86 EMGTSLSSSLPSSWLTQSNNHANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEV 150
            |:.....:..|...||::      |.:|:.:|..||:.:||..|..|..:.|:::|.|:||||..
Mouse   465 ELTVDCMTERPGGKLTRA------SRILNTILSNYDHKLRPGIGEKPTVVTVEVIVNSLGPISTP 523

  Fly   151 DMTYSMDCYFRQSWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRI 215
            ||.||:|..|.|:|.|:||.:....:||.|..::::::|.|||:|.|.|::..:.||.||:...|
Mouse   524 DMEYSIDIIFHQTWYDERLRYNDTFETLILHGNVVSQLWIPDTFFRNSKRTQEYDITIPNQMALI 588

  Fly   216 YQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKL 280
            :::|:||||.|:||.|.|.:::.:||||...|||.|.||.|..|::||:|...:..:......||
Mouse   589 HKDGKVLYSVRMTIDARCSLHMLNFPMDSHSCPLSFSSFSYDDSEMIYKWENFKLEINAKNTWKL 653

  Fly   281 SQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDK 345
            .:||...  ..|.|:|:         ..||.:       ..|||.|
Mouse   654 LEFDFTG--VNNKTEII---------STPFGD-------FMVMTFF------------------- 681

  Fly   346 GAFGTGRDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSW 410
                                                   |::.|..|..:.|.|.|..:..:|||
Mouse   682 ---------------------------------------FNVSRRFGFIVFQNYVPSSVTTMLSW 707

  Fly   411 VSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVV 475
            ||||:..||.|.|.|:|:::||||..||..:..:.|:|||.|||||::.:.|...|.|:|:|||:
Mouse   708 VSFWIKIEAAAARASVGVSSVLTMATLGTLSCKNFPRVSYLTALDFYIAICFVLCFCTLLEFAVL 772

  Fly   476 HYYTKYGSGECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGML 540
            ::.|                          .::.:.....|:|::             ||.
Mouse   773 NFLT--------------------------YNNIKRQASLKVYQL-------------PTN---- 794

  Fly   541 TSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAA 605
            :..|.|.|.|               .|.|...||.:.:.::....::...|           :.|
Mouse   795 SRANARTRAR---------------ARTRARARARARQQQEVFVCEIVTYE-----------ENA 833

  Fly   606 AQAARISPPTGGRRRMSYYRREEMEARRKGKRTPQYN------------------------SVSK 646
            .:..:.||.:         ||.:...||.|:....:.                        .|.:
Mouse   834 EEGYQWSPRS---------RRPQCPWRRCGRSYVCFRVLRKYFCMAPGCEGGSWQRGRICIHVYR 889

  Fly   647 IDRASRIVFPLLFILINVFYW 667
            :|..||::||:.|...||.||
Mouse   890 LDNYSRVLFPITFFFFNVLYW 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	79/215 (37%)
		LIC	111..670	CDD:273305	153/581 (26%)
		Neur_chan_memb	398..667	CDD:280999	68/292 (23%)
Gabre	NP_059065.2	Neur_chan_LBD	482..687	CDD:280998	81/286 (28%)
		LIC	484..912	CDD:273305	153/581 (26%)
		Neur_chan_memb	696..910	CDD:280999	68/291 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X127
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.010