Protein Alignment Grd and Gabrb3

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001033790.1
• Gene: Gabrb3 / 14402
• MGIID: 95621
• Length: 473
• Species: Mus musculus
• Alignment Length: 646
• Identity: 176/646 - (27%)
• Similarity: 269/646 - (41%)
• Gaps: 192/646 - (29%)

  Fly    45 CCLLMLCIYPNAWPWSIGP-GSGPFSVSADSIKGRGDTHRLGEMGTSLSSSLPSSWLTQSNNHAN 108
            |..|...:.|....|::|. ||.|.||:                              ...|.:.
Mouse     2 CSGLQALLLPIWLSWTLGTRGSEPSSVN------------------------------DPGNMSF 36

  Fly   109 ISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAFEG 173
            :.|.:|.||:|||..:||||||||..:.::|.:.|:..:|||:|.|::..||:|.|.|||||:.|
Mouse    37 VKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSG 101

  Fly   174 AQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMNLA 238
            ....|.|...:..::|.|||||.|.|:|::|.:|..|:.:|::.:|.|||..|:|..|.|.|:|.
Mouse   102 IPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR 166

  Fly   239 DFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVYKAAAP 303
            .:|:|.|.|.|:..|:||||.|:.:.|......|...|.::|.||.:|:
Mouse   167 RYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVE---------------- 215

  Fly   304 RPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTGLSGTI 368
                        .|..|:.:                       .|.||
Mouse   216 ------------HRLVSRNV-----------------------VFATG----------------- 228

  Fly   369 TLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTVLT 433
                    .|..|.::|.|:|::|.|::|.|.|..|:.:|||||||:|.:|:|.||:||||||||
Mouse   229 --------AYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLT 285

  Fly   434 MTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEELDSESG 498
            ||.:....|..|||:.|..|:|.::...|.|:|..:|::|.|:|.. :|.|
Mouse   286 MTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIF-FGRG-------------- 335

  Fly   499 ESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMKLLGLF 563
                                               |.|...|..:..:.:|.
Mouse   336 -----------------------------------PQRQKKLAEKTAKAKND------------- 352

  Fly   564 DWRRRRKPPRAD-------SDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARISPPTGGRRR- 620
              |.:.:..|.|       :..|..:|..::..:...|.::|.:...:..|..:.|.|..|..|
Mouse   353 --RSKSEINRVDAHGNILLAPMDVHNEMNEVAGSVGDTRNSAISFDNSGIQYRKQSMPKEGHGRY 415

  Fly   621 ---------MSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYLS 672
                     .::.||...:.:.|   .|....|:.|||.||||||..|.|.|:.||..|::
Mouse   416 MGDRSIPHKKTHLRRRSSQLKIK---IPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	77/215 (36%)
		LIC	111..670	CDD:273305	164/575 (29%)
		Neur_chan_memb	398..667	CDD:280999	74/285 (26%)
Gabrb3	NP_001033790.1	LIC	4..471	CDD:273305	174/640 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810