Protein Alignment Grd and Gabrb2

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001334243.1
• Gene: Gabrb2 / 14401
• MGIID: 95620
• Length: 512
• Species: Mus musculus
• Alignment Length: 587
• Identity: 177/587 - (30%)
• Similarity: 268/587 - (45%)
• Gaps: 123/587 - (20%)

  Fly   104 NNHANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKR 168
            :|.:.:.|.:|.||:|||..:||||||||..:.::|.:.|:..:|||:|.|::..||:|:|.|||
Mouse    31 SNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKR 95

  Fly   169 LAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGC 233
            |::......|.|...:..::|.|||||.|.|:|::|.:|..|:.:|::.:|.|||..|:|..|.|
Mouse    96 LSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAAC 160

  Fly   234 PMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVY 298
            .|:|..:|:|.|.|.|:..|:||||.|:.:.|..:...|.....::|.||.:||          |
Mouse   161 MMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVD----------Y 215

  Fly   299 KAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTG 363
            |..                 |.||:                        |.||
Mouse   216 KLI-----------------TKKVV------------------------FSTG------------ 227

  Fly   364 LSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGI 428
                         .|..|.::|.|:|::|.|::|.|.|..|:.:|||||||:|.:|:|.||:|||
Mouse   228 -------------SYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 279

  Fly   429 TTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEEL 493
            |||||||.:....|..|||:.|..|:|.::...|.|:|..:|::|:|:|.. :|.|      .:.
Mouse   280 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIF-FGRG------PQR 337

  Fly   494 DSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMK 558
            ..::.|..........|.......|:.|..:.........||  |.| |..||..|....|::|
Mouse   338 QKKAAEKAANANNEKMRLDVNKMFYKDIKQNGTQYRSLWDPT--GDL-SPTRRTTNYDFSLYTM- 398

  Fly   559 LLGLFDWRRRRKPPRADSDEDEDDEQTQLR-ANEAPTTSAAAA-----AAQAAAQAARISPPTGG 617
                              |..|:...:.|. .||..|:.|...     :...|..|:.|.....|
Mouse   399 ------------------DPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAG 445

  Fly   618 RRRMSYYRR--EEMEARRKGK----------RTPQYNSVSKIDRASRIVFPLLFILINVFYWYGY 670
            ..|.|:.|.  |...|::|.:          ..|....|:.|||.|||.||::|...|:.||..|
Mouse   446 LPRHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 510

  Fly   671 LS 672
            ::
Mouse   511 VN 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	78/215 (36%)
		LIC	111..670	CDD:273305	175/576 (30%)
		Neur_chan_memb	398..667	CDD:280999	84/286 (29%)
Gabrb2	NP_001334243.1	LIC	9..510	CDD:273305	176/583 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810