Protein Alignment Grd and Gabrb1

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_032095.1
• Gene: Gabrb1 / 14400
• MGIID: 95619
• Length: 474
• Species: Mus musculus
• Alignment Length: 583
• Identity: 182/583 - (31%)
• Similarity: 263/583 - (45%)
• Gaps: 139/583 - (23%)

  Fly    92 SSSLPSSWLTQSNNHANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSM 156
            ||:.||       |.:.:.|.:|.||:|||..:||||||||..:.:.|.|.|:..:|||:|.|::
Mouse    27 SSNEPS-------NMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTL 84

  Fly   157 DCYFRQSWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRV 221
            ..||:|||.||||::.|....|.|...:..::|.|||||.|.|:|::|.:|..|:.:|::.:|.|
Mouse    85 TMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTV 149

  Fly   222 LYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLV 286
            ||..|:|..|.|.|:|..:|:|.|.|.|:..|:||||.|:.:.||.....|.....::|.||.:|
Mouse   150 LYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIV 214

  Fly   287 DCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTG 351
            |          ||..:.:.:                                         |.||
Mouse   215 D----------YKMVSKKVE-----------------------------------------FTTG 228

  Fly   352 RDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLN 416
                                     .|..|.::|.|:|::|.|::|.|.|..|:.:|||||||:|
Mouse   229 -------------------------AYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWIN 268

  Fly   417 REATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKY 481
            .:|:|.||:||||||||||.:....|..|||:.|..|:|.::...|.|:|..:|::|.|:|.. :
Mouse   269 YDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIF-F 332

  Fly   482 GSGECYFIIEELDSESGES---ETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSR 543
            |.|.......:.|..:.|.   |...:..|..|:        |.||...|
Mouse   333 GKGPQKKGASKQDQSANEKNRLEMNKVQVDAHGN--------ILLSTLEI--------------- 374

  Fly   544 NRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQA 608
                ||...|  |..|.|:.|       |:| :....|....|.|   .|.:|...    .....
Mouse   375 ----RNETSG--SEVLTGVSD-------PKA-TMYSYDSASIQYR---KPLSSREG----FGRGL 418

  Fly   609 ARISPPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYL 671
            .|...|..||.|    ||    |.:...:.|....|:.||:.||:.||:.|.|.||.||..|:
Mouse   419 DRHGVPGKGRIR----RR----ASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYV 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	79/215 (37%)
		LIC	111..670	CDD:273305	176/561 (31%)
		Neur_chan_memb	398..667	CDD:280999	84/271 (31%)
Gabrb1	NP_032095.1	LIC	9..472	CDD:273305	181/580 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810