Protein Alignment Grd and Gabrg1

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_542153.1
• Gene: Gabrg1 / 140674
• RGDID: 621732
• Length: 465
• Species: Rattus norvegicus
• Alignment Length: 580
• Identity: 184/580 - (31%)
• Similarity: 260/580 - (44%)
• Gaps: 166/580 - (28%)

  Fly    94 SLPSSWLTQSNNH-ANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMD 157
            ::..:|:.....| .:|:::|::||:||||.:|||.|..|..||.|:.|.|:||:..::|.|::|
  Rat    48 TMNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTID 112

  Fly   158 CYFRQSWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVL 222
            ..|.|:|.|.||.|......|.|:.:|:.:||.|||:|.|.::|..|.|||||:.:||:.:||||
  Rat   113 IIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVL 177

  Fly   223 YSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVD 287
            |:.||||.|.|.:.|.:||||...|||:|.|:||..:::.|:|.|....||..:..:|.||..|
  Rat   178 YTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFV- 241

  Fly   288 CPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGR 352
                                                                ||:
  Rat   242 ----------------------------------------------------GLR---------- 244

  Fly   353 DATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNR 417
                   ::|.:|.||:      .:|.::.:.|.|.|.||.|.||.|.||.|.|||||||||:|:
  Rat   245 -------NSTEISHTIS------GDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINK 296

  Fly   418 EATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYG 482
            :|...|.|||||||||||.|...||..||||||.||:|.||.:.|.|:||.::::..:||:|...
  Rat   297 DAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNN 361

  Fly   483 SGECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRP 547
            .|      :.......:|:|........|||      :||::  .||||
  Rat   362 KG------KTTRDRKLKSKTSVSPGLHAGST------LIPMN--NISMP---------------- 396

  Fly   548 RNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQ-LRANEAPTTSAAAAAAQAAAQAARI 611
                                          :.|||...| |...:..|........:
  Rat   397 ------------------------------QGEDDYGYQCLEGKDCATFFCCFEDCR-------- 423

  Fly   612 SPPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYL 671
               ||..|....:.|                 ::|||..|||.||..|.|.|:.||.|||
  Rat   424 ---TGSWREGRIHIR-----------------IAKIDSYSRIFFPTAFALFNLVYWVGYL 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	80/215 (37%)
		LIC	111..670	CDD:273305	178/559 (32%)
		Neur_chan_memb	398..667	CDD:280999	81/269 (30%)
Gabrg1	NP_542153.1	Neur_chan_LBD	65..270	CDD:280998	90/280 (32%)
		LIC	66..462	CDD:273305	178/559 (32%)
		Neur_chan_memb	277..459	CDD:280999	81/269 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	199	1.000	Domainoid score	I2964
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X127
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.010