Protein Alignment Grd and LOC1281130

DIOPT Version :10

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_321068.3
• Gene: LOC1281130 / 1281130
• VectorBaseID: AGAMI1_001548
• Length: 212
• Species: Anopheles gambiae
• Alignment Length: 305
• Identity: 67/305 - (21%)
• Similarity: 109/305 - (35%)
• Gaps: 119/305 - (39%)

  Fly   367 TITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTV 431
            ||...|.:   ::.|.|.|:|:|.:|..|...|.|..|:||:||:|||:..||...||:||:|::
Mosquito    27 TIEYSTGN---FTCLAVVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSL 88

  Fly   432 LTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEELDSE 496
            ||:.....:::..||.|||..|:|.::.....|:|.::::||||:.|
Mosquito    89 LTLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVVNNY------------------ 135

  Fly   497 SGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMKLLG 561
            .|...|:.:    :|.::..:.|.|..                    |:...|:.|
Mosquito   136 MGPVATKAM----KGYSDEDLSEAIDF--------------------NKNGYNKDH--------- 167

  Fly   562 LFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARISPPTGGRRRMSYYRR 626
                                      |::|.|.........:.|.
Mosquito   168 --------------------------RSSEVPRYDTFCHGRETAL-------------------- 186

  Fly   627 EEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYL 671
                               .||:.||..||..|.::||.||..:|
Mosquito   187 -------------------CIDKFSRFFFPFSFFILNVTYWTTFL 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	LIC	111..670	CDD:455710	66/302 (22%)
		LGIC_ECD_GABAR_GRD-like	132..300	CDD:349808
		Cys-loop	233..247	CDD:349808
LOC1281130	XP_321068.3	LGIC_ECD	<1..47	CDD:475126	7/22 (32%)
		LGIC_TM_anion	50..>136	CDD:349851	34/103 (33%)
		TM1 helix	50..73	CDD:349851	11/22 (50%)
		TM2 helix	77..101	CDD:349851	7/23 (30%)
		TM3 helix	109..135	CDD:349851	8/25 (32%)