Protein Alignment Grd and Glra3

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_446176.3
• Gene: Glra3 / 114516
• RGDID: 621229
• Length: 480
• Species: Rattus norvegicus
• Alignment Length: 683
• Identity: 192/683 - (28%)
• Similarity: 277/683 - (40%)
• Gaps: 232/683 - (33%)

  Fly     4 MPATRDASGSGDASTDLIAARSLSSHQGQRSNLRIFKLLIS------CCLLMLCIYPNAWPWSIG 62
            ||..|..||||      |:.|.:       :::|.|:.|:|      ..||:..:...
  Rat     1 MPWIRLFSGSG------ISFRIM-------AHVRHFRTLLSGFYFWEAALLLSLVATK------- 45

  Fly    63 PGSGPFSVSADSIKGRGDTHRLGEMGTSLSSSLPSSWLTQSNNHANISELLDNLL---RGYDNSI 124
                                   |..::.|.|.|.|          .|:.||.|:   .|||..|
  Rat    46 -----------------------ETNSARSRSAPMS----------PSDFLDKLMGRTSGYDARI 77

  Fly   125 RPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAF-EGAQDTLALSVSMLARI 188
            ||:|.|||..:..:|.:.|.|.|:|..|.|.::.:.||.|.|.|||: |...|:|.|..|||..|
  Rat    78 RPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 142

  Fly   189 WKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGS 253
            ||||.:|.|.|.:..|.:||.||.:||::||.||||.|||:...|||:|.:||||:|.|.::..|
  Rat   143 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLES 207

  Fly   254 FGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRP 318
            ||||.:|:|:.|..| .||.:||.:.|.||.|.:                        .||
  Rat   208 FGYTMNDLIFEWQDE-APVQVAEGLTLPQFLLKE------------------------EKD---- 243

  Fly   319 TSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTGLSGTITLETNHPSEYSMLMV 383
                                  |:.....:.||:                         ::.:.|
  Rat   244 ----------------------LRYCTKHYNTGK-------------------------FTCIEV 261

  Fly   384 NFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKV 448
            .|||:|.||.:|||:|.|..|:|:|||||||:|.:|...||:||||||||||.....:|..||||
  Rat   262 RFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKV 326

  Fly   449 SYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEELDSESGESETEPLTSDFRGST 513
            ||..|:|.::.:...|:|:.:|::|.|::.::..        :||
  Rat   327 SYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQH--------KEL-------------------- 363

  Fly   514 ESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDE 578
                                        .|.||.|..:...::::....|              .
  Rat   364 ----------------------------LRFRRKRKNKTEAFALEKFYRF--------------S 386

  Fly   579 DEDDEQTQLRAN-----EAPTTSAA-AAAAQAAAQAARISPPTGGRRRMSYYRREEMEARRKGKR 637
            |.|||..:.|.:     ..|...|. ....:....|.::.|.:....|..:..|
  Rat   387 DTDDEVRESRFSFTAYGMGPCLQAKDGVVPKGPNHAVQVMPKSADEMRKVFIDR----------- 440

  Fly   638 TPQYNSVSKIDRASRIVFPLLFILINVFYWYGY 670
                  ..|||..||..|||.|::.|:|||..|
  Rat   441 ------AKKIDTISRACFPLAFLIFNIFYWVIY 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	88/219 (40%)
		LIC	111..670	CDD:273305	170/568 (30%)
		Neur_chan_memb	398..667	CDD:280999	68/274 (25%)
Glra3	NP_446176.3	LIC	28..467	CDD:273305	179/641 (28%)
		Neur_chan_LBD	63..269	CDD:280998	95/281 (34%)
		Neur_chan_memb	276..464	CDD:280999	68/274 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810