Protein Alignment Grd and gabrd

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_017951272.2
• Gene: gabrd / 100488161
• XenbaseID: XB-GENE-988598
• Length: 450
• Species: Xenopus tropicalis
• Alignment Length: 597
• Identity: 156/597 - (26%)
• Similarity: 258/597 - (43%)
• Gaps: 164/597 - (27%)

  Fly    74 SIKGRGDTHRLGEMGTSLSSSLPSSWLTQSNNHANISELLDNLLRGYDNSIRPDFGGPPATIEVD 138
            :::.||.:..:||.   :.|::..||:..          ||:|::||..:.||..||.|..:.||
 Frog    16 ALEDRGHSEDIGEF---IGSNIEISWVPN----------LDDLMKGYARNFRPGIGGAPVIVAVD 67

  Fly   139 IMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYL 203
            :.|.|:..||||:|.|:|..:..|||.|:||::.....||.|....:.::|.|||:..|.|.::.
 Frog    68 VEVTSIDHISEVNMEYTMTVFLHQSWRDERLSYNHTNKTLGLDSRFVEKLWLPDTFIVNAKSAWF 132

  Fly   204 HTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKE 268
            |.:|..||.:|:..:|.:|||||:|....|.|:|..:|||.|:|.|:..|:||::.|::|||::.
 Frog   133 HDVTVENKLIRLQPDGVILYSSRITSTVSCDMDLTKYPMDEQECMLELESYGYSSEDILYRWSEN 197

  Fly   269 RPPVAIAEDMKLSQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKN 333
            :......:.::|:||.:.:          |:                              ..||
 Frog   198 QEKNHGLDKIELAQFTVTN----------YR------------------------------FTKN 222

  Fly   334 QHVRGTGLKLDKGAFGTGRDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQV 398
            :.:    ||                               ...|:..|.::|||:|:.|.::|:.
 Frog   223 EMI----LK-------------------------------SAGEFPRLSLHFHLRRNRGVYIIES 252

  Fly   399 YGPCCLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFG 463
            |.|..|||.:||||||:::.|...|||||||||||||.|.:.|||.||:.|...|||.:..:.:.
 Frog   253 YVPSILLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARTSLPRASAVKALDVYFLICYV 317

  Fly   464 FIFATILQFAVVHYYTKYGSGECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAI 528
            |:||.::::|..||...      |...|::.:::.:...:...::.:       |.::.||:..:
 Frog   318 FVFAALVEYAFAHYSAD------YIKKEKVKTKASKKNKQVQMNEGQ-------YAIVLLSLSIL 369

  Fly   529 SMPPPPTRLGMLTSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAP 593
            .|....|.:           |:.|
 Frog   370 GMDQSLTLI-----------NKHH----------------------------------------- 382

  Fly   594 TTSAAAAAAQAAAQAARISPPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLL 658
                     .|....||:......:.::....:.|.|:|.|....|  .....||..:|.|||..
 Frog   383 ---------FATQNEARLEGMRKDKLQICRDPKPEKESRLKSLLRP--IEADSIDVYARAVFPAA 436

  Fly   659 FILINVFYWYGY 670
            |..:|:.||..|
 Frog   437 FAAVNIIYWVAY 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	68/215 (32%)
		LIC	111..670	CDD:273305	148/558 (27%)
		Neur_chan_memb	398..667	CDD:280999	66/268 (25%)
gabrd	XP_017951272.2	LIC	42..448	CDD:273305	148/556 (27%)
		LGIC_ECD	61..244	CDD:355788	68/257 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6745
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910