Protein Alignment Grd and gabrr3

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_017947352.2
• Gene: gabrr3 / 100487991
• XenbaseID: XB-GENE-6039478
• Length: 481
• Species: Xenopus tropicalis
• Alignment Length: 664
• Identity: 167/664 - (25%)
• Similarity: 263/664 - (39%)
• Gaps: 225/664 - (33%)

  Fly    47 LLMLCIYPNAWPWSIGPG-----SGPFSVSADSIKGRGDTHRLGEMGTSLSSSLPSSWLTQSNNH 106
            ::.|.:..:.||.::..|     ..|:|..        ..|.            |...:.|...|
 Frog     4 IIKLLLLTSLWPGAVLSGFHSLRQKPYSPQ--------HLHH------------PHQVVNQEEEH 48

  Fly   107 ANISELLDN----------------------LLR--GYDNSIRPDFGGPPATIEVDIMVRSMGPI 147
            :..:.:.||                      |||  .:|.::||.|||....:.:|:.:.|:..|
 Frog    49 SQPAAMRDNRKNASKMRRIDSTKVRQMKSEQLLRIDDHDFAMRPGFGGSAIPVGIDVQIESIDSI 113

  Fly   148 SEVDMTYSMDCYFRQSWVDKRLAFEGAQD-TLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNK 211
            |||||.::|..|.|..|.|:||:|:...: ::.....::.:||.||.:|.:.|:|::|..|..|.
 Frog   114 SEVDMDFTMTLYLRHYWKDERLSFQSTNNRSMTFDGRLIKKIWVPDVFFVHSKRSFIHDTTMENI 178

  Fly   212 FVRIYQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAE 276
            .:|:|.:|.||:|.|:|:.|.|.|:.:.||:|.|.|.|:..|:.|...|::..|.:....:...|
 Frog   179 MLRVYPDGNVLFSLRITVTAMCFMDFSRFPLDTQNCSLELESYAYNEEDLMLYWKRGNESLKTDE 243

  Fly   277 DMKLSQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGL 341
            .:.||||.:.:..|.|                                               ||
 Frog   244 HIALSQFFIEEFSASN-----------------------------------------------GL 261

  Fly   342 KLDKGAFGTGRDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLV 406
                 ||          .|:||.             |:.|.:||.|:||:..||:|.|.|..|:|
 Frog   262 -----AF----------YSSTGW-------------YNRLFINFILRRHIFFFLLQSYFPAMLMV 298

  Fly   407 VLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQ 471
            :|||||||::|.|...||||||||||||:.:.......:|:|||..|:|.::::||.|:|.::::
 Frog   299 MLSWVSFWIDRRAVPARVSLGITTVLTMSTIITGVSASMPQVSYIKAVDVYLWISFLFVFLSVIE 363

  Fly   472 FAVVHYYTKYGSGECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTR 536
            :|.|:|.|
 Frog   364 YAAVNYLT--------------------------------------------------------- 371

  Fly   537 LGMLTSRNRRPRNRR---------HGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEA 592
                |:..|:...||         ..:.:|...|.|.          |||.|     .....:..
 Frog   372 ----TAEERKQLKRRGKSSATLNLEAVQAMAFDGCFH----------DSDAD-----LNFSMHSE 417

  Fly   593 PTTSAAAAAAQAAAQAARISPPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPL 657
            .::|...||:.|...|.|:             ||::......|:...:.|.|  ||..|||:||.
 Frog   418 ESSSRGRAASVATLDAMRV-------------RRKKSIRGNFGRIILENNHV--IDTYSRIIFPT 467

  Fly   658 LFILINVFYWYGYL 671
            ::|:.|.|||..||
 Frog   468 VYIVFNFFYWGAYL 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	65/240 (27%)
		LIC	111..670	CDD:273305	155/592 (26%)
		Neur_chan_memb	398..667	CDD:280999	71/277 (26%)
gabrr3	XP_017947352.2	LIC	77..480	CDD:273305	153/568 (27%)
		LGIC_ECD	98..283	CDD:355788	67/259 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910