DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Grd and LOC100333913

DIOPT Version :9

Sequence 1:	NP_524131.1	Gene:	Grd / 39984	FlyBaseID:	FBgn0001134	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	XP_002666117.5	Gene:	LOC100333913 / 100333913	-ID:	-	Length:	175	Species:	Danio rerio

Alignment Length:	256	Identity:	62/256 - (24%)
Similarity:	102/256 - (39%)	Gaps:	90/256 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   434 MTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKY-----GSGECYFIIEEL 493
            ||.|.:.||..||||:|.||:|:|:.:.:.|:|:.:::||.|:|:||.     |..|.    :|:
Zfish     1 MTTLSISARNSLPKVAYATAMDWFMAVCYAFVFSALIEFATVNYFTKRSWAWDGQKEA----QEM 61

  Fly   494 DSESGESETEPLTSDFR--GSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWS 556
            ......|.::...:.|.  |:|                                         :|
Zfish    62 RRRESASFSKKTNNTFNIVGTT-----------------------------------------YS 85

  Fly   557 MKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARISPPTGGRRRM 621
            |.::                   :|...|.:..:..||||               :||...|.
Zfish    86 MSVV-------------------KDPGLTTISKSATPTTS---------------TPPQPVRE-- 114

  Fly   622 SYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYLSRSSRILANTP 682
              .|..:|:.....:....||.|||:|:.|||:||:||.:.|:.||..|::|...|..::|
Zfish   115 --VRLPKMDGEYVPEGRKSYNRVSKVDKISRIIFPVLFFIFNLGYWATYVNRKPTIERSSP 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998
		LIC	111..670	CDD:273305	58/242 (24%)
		Neur_chan_memb	398..667	CDD:280999	56/239 (23%)
LOC100333913	XP_002666117.5	Neur_chan_memb	1..158	CDD:308533	56/239 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010