Protein Alignment Grd and gabrb1

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_002664179.2
• Gene: gabrb1 / 100331377
• ZFINID: ZDB-GENE-090313-230
• Length: 484
• Species: Danio rerio
• Alignment Length: 604
• Identity: 175/604 - (28%)
• Similarity: 274/604 - (45%)
• Gaps: 140/604 - (23%)

  Fly    79 GDTHRLG------EMGTSLSSSLPSSWLTQSNNHANISELLDNLLRGYDNSIRPDFGGPPATIEV 137
            ||..|.|      .:..:|..|.|:..:.:.:|.:.:...:|.||:|||..:||||||||..:.:
Zfish     9 GDQWRAGIFCLLVLVALTLGRSPPAHSVNEPSNMSYVKVTVDKLLKGYDIRLRPDFGGPPVDVGM 73

  Fly   138 DIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSY 202
            .|.:.|:..:|||:|.|::..||:|||.||||::.|....|.|...:..::|.|||||.|.|:|:
Zfish    74 SIDISSIDMVSEVNMDYTITMYFQQSWRDKRLSYTGIPLNLTLDNRVADQLWVPDTYFINDKKSF 138

  Fly   203 LHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNK 267
            :|.:|..|:.:|::.:|.|||..|:|..|.|.|:|..:|:|.|.|.|:..|:||||.|:.:.| :
Zfish   139 VHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW-Q 202

  Fly   268 ERPPVAIAEDMKLSQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAK 332
            ....|...::::|.||.::|          ||..:
Zfish   203 GGSSVTGVDNIELPQFSIID----------YKTLS------------------------------ 227

  Fly   333 NQHVRGTGLKLDKGAFGTGRDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQ 397
                       .|..|.||                         .|..|.::|.|:|::|.|::|
Zfish   228 -----------KKVVFATG-------------------------SYPRLSLSFKLKRNIGYFILQ 256

  Fly   398 VYGPCCLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSF 462
            .|.|..|:.:|||||||:|.:|:|.||:||||||||||.:....|..|||:.|..|:|.::...|
Zfish   257 TYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDIYLMGCF 321

  Fly   463 GFIFATILQFAVVHYYTKYGSGECY--FIIEEL---DSESGESETEPLTSDFRGSTESKIYEVIP 522
            .|:|..:|::|.|:|.. :|.|...  .:.|:.   ::|....|:..:..|..||        ||
Zfish   322 VFVFLALLEYAFVNYIF-FGRGPHLQKKVAEKAAKSNNEKSRLESNKVQVDVHGS--------IP 377

  Fly   523 LSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQL 587
            |:...:.: .....||.|..    |||.           :|.:               |....|.
Zfish   378 LTNLDLRL-SGAEMLGALGD----PRNT-----------MFSY---------------DSASIQY 411

  Fly   588 RANEAPTTSAAAAAAQAAAQAARISPPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSKIDRASR 652
            |   .|.|.........|:....::|      :.|..||...:.:.|   .|....|:.||:.||
Zfish   412 R---KPLTGRDLYGRPTASIERPLAP------KKSRLRRRAAQLKVK---IPDLTDVNAIDKWSR 464

  Fly   653 IVFPLLFILINVFYWYGYL 671
            ::||:.:...|:.||..|:
Zfish   465 VIFPITYTFFNLVYWLYYV 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	75/215 (35%)
		LIC	111..670	CDD:273305	166/563 (29%)
		Neur_chan_memb	398..667	CDD:280999	77/273 (28%)
gabrb1	XP_002664179.2	LIC	19..482	CDD:273305	170/591 (29%)
		Neur_chan_LBD	49..250	CDD:280998	84/277 (30%)
		Neur_chan_memb	257..479	CDD:280999	77/273 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810