DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir75c and GLR2.2

DIOPT Version :9

Sequence 1:	NP_649013.3	Gene:	Ir75c / 39983	FlyBaseID:	FBgn0261401	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_180048.1	Gene:	GLR2.2 / 817008	AraportID:	AT2G24720	Length:	920	Species:	Arabidopsis thaliana

Alignment Length:	212	Identity:	41/212 - (19%)
Similarity:	75/212 - (35%)	Gaps:	53/212 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 LHYIWCGTWSVQDAFGGAIGMLTNESAEL-CTTPFVPSWNRLHYLHPMTEQAQFRAVCMFRTPHN 313
            :|.::.|.:   ||..|...:|.|.|:.: .|.||:.|...|  :.|:.::.:       |...:
plant   522 VHQVYLGQF---DAVVGDTTILANRSSFVDFTLPFMKSGVGL--IVPLKDEVK-------RDKFS 574

  Fly   314 AGIKAAVFLEPFMPSVWFAFAGLLIFAGVLLWMIFHLER--------------HWMQ-RCLDFIP 363
                   ||:|....:|..........|:.:|.:.|...              .|.. ..:.|.|
plant   575 -------FLKPLSIELWLTTLVFFFLVGISVWTLEHRVNSDFRGPANYQASTIFWFAFSTMVFAP 632

  Fly   364 SLLSSCLISFGAACIQGSYLMPKSAGGRLAFIAVMLTSFLMYNYYTSIVVSTLLGSPVRSNIRTI 428
               ...::||||..:..::.          |:.::||     ..||:.:.|.|....:...|.::
plant   633 ---RERVLSFGARSLVVTWY----------FVLLVLT-----QSYTASLASLLTSQQLNPTITSM 679

  Fly   429 QQLADSSLDVGFDTVPF 445
            ..|......||:....|
plant   680 SSLLHRGETVGYQRTSF 696

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	23/133 (17%)
GLR2.2	NP_180048.1	PBP1_GABAb_receptor	33..412	CDD:107361
		ANF_receptor	47..392	CDD:279440
		HisJ	438..>587	CDD:223904	19/83 (23%)
		GluR_Plant	452..801	CDD:270404	41/212 (19%)
		Lig_chan	582..819	CDD:278489	23/133 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000