Protein Alignment Ir75c and grik5

DIOPT Version :10

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001315085.1
• Gene: grik5 / 798791
• ZFINID: ZDB-GENE-070821-6
• Length: 1067
• Species: Danio rerio
• Alignment Length: 542
• Identity: 111/542 - (20%)
• Similarity: 208/542 - (38%)
• Gaps: 104/542 - (19%)

  Fly   111 NFTKLTQLFEGANLSLNADVTYVSREDEERFILHDVYNKGSHLGGKLNITV---DQTLQCNRS-- 170
            |:.::.: ::|    |...|.:.|:.....:.|| :..|  |.||...|.:   :.||..|.:
Zfish   361 NYLRMVE-YDG----LTGRVEFNSKGQRTNYTLH-ILEK--HRGGHKEIGIWYSNNTLLMNSTSL 417

  Fly   171 HCQVKEYLSELHLRPRLQHRMDLSSVTFRLAALVSVLPINSSEEELLEFLNSDRDSHMDSISRIG 235
            ...|.|.|:...|           .:|..|.....:..||..|.|                   |
Zfish   418 DINVSETLANKSL-----------IITTILENPYVMRKINYQEFE-------------------G 452

  Fly   236 NR--------LIMHTQEILGF--KLHYIWCGTWSVQDAFG---GAIGMLTNESAELCTTPFVPSW 287
            |.        ::....:||.|  ::..:..|.:...:..|   |.:|.|.|..|:|....|..:.
Zfish   453 NEQYEGFCVDMLRELSDILKFTYRIKLVDDGLYGAPEPNGSWTGMVGELINRKADLAVAAFTITS 517

  Fly   288 NR---LHYLHP-MTEQAQFRAVCMFRTPHNAGIKAAV--FLEPFMPSVWFAFAGLLIFAGVLLWM 346
            .|   :.:..| ||    .....::|.  :.|.|...  ||:||.|:||.......:....:|::
Zfish   518 EREKVIDFSKPFMT----LGISILYRV--HIGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFL 576

  Fly   347 IFHLERH-WM--QRCL----DFIP---SLLSSCLISFGAACIQGSYLMPKSAGGRL------AFI 395
            ...|..: |.  ..||    |.:.   :|.:|.....|....|||.:||::...|.      ||.
Zfish   577 SARLSPYEWYNPHPCLRERRDLLENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFT 641

  Fly   396 AVMLTSFLMYNYYTSIVVSTLLGSPVRSNIRTIQQLADSSLDVGFDTV--PFTKTYLVSSPRPDI 458
            .::::|      ||:.:.:.|....:...|.:...|||.: ::.:.|:  ..|.|:.::|.....
Zfish   642 LIIISS------YTANLAAFLTVQRMEVPIESPDDLADQT-NIQYGTIHGGSTMTFFMNSRYQTY 699

  Fly   459 RSLYKQKVESKRDPNSVWLSPEEGVIRVRDQPGFVYTSEASFMYHFVEKHYLPREISDLNEIILR 523
            :.::....  .:.|:....|.|||:.|       |..|:.:|:.......|......:|.:|...
Zfish   700 QRMWNYMY--SKQPSVFVKSTEEGIAR-------VVNSKYAFLLESTMNEYHRSLNCNLTQIGGL 755

  Fly   524 PESAVYGM-VHLNSTYRQLLTQLQVRMLETG-ITSKQSRFFSKTKLHTFSNSFVIQVGMEYAAPL 586
            .::..||: :.|.|.:|..|:...:::.|.. :...:.|::...|.....:.....:|||....:
Zfish   756 LDTKGYGIGMPLGSPFRDELSLAVLQLQENNRLEILKRRWWEGGKCPKEEDHRAKGLGMENIGGI 820

  Fly   587 FISLLVAYFLALLILILEICWA 608
            |:.|:....:|:.:.::|..|:
Zfish   821 FVVLICGLIIAVFVAVMEFVWS 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..>508	CDD:459656	40/197 (20%)
grik5	NP_001315085.1	PBP1_iGluR_Kainate_KA1_2	36..414	CDD:380616	14/60 (23%)
		Periplasmic_Binding_Protein_Type_2	427..797	CDD:473866	84/421 (20%)