Protein Alignment Ir75c and grin3a

DIOPT Version :9

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_009303361.1
• Gene: grin3a / 564832
• ZFINID: ZDB-GENE-130530-780
• Length: 1111
• Species: Danio rerio
• Alignment Length: 622
• Identity: 130/622 - (20%)
• Similarity: 223/622 - (35%)
• Gaps: 132/622 - (21%)

  Fly    82 DKAELVTNQSSRARLYNQNL-------HWLLYDEAGNFTKLTQL--------FEGAN--LSLNAD 129
            |..|||......|...:..|       :.|...||.|.|..|.|        |:|.:  :|:..:
Zfish   395 DALELVARAVGSAATVSPQLALIPGTTNCLARLEAKNLTSGTFLSRYMASTSFDGLSGCISVQEE 459

  Fly   130 VTYVSREDEERFI---LHDVYNK------GSHLGGKLNITVDQTLQCNRSHCQVK---EYLSELH 182
            .|.:|  :...||   .||...|      ||...||  :.:|..:..|:...|..   .:.|.||
Zfish   460 STIIS--ESHHFIWNLQHDPIGKPMWTRLGSWKHGK--VVMDYGVWPNKRRSQPGADWRHSSRLH 520

  Fly   183 LR--PRLQH----RMDLSSVTFRLAALVSVLPINSSEEELLEFLNSDRDSHMDSISRIGNR---- 237
            ||  ..::|    ..|:.......|..:.:.|: :::..|||.|........|::.....:
Zfish   521 LRVVTLVEHPFVFTRDVDDEGLCPAGQLCLDPL-TNDTALLESLFQGLQGANDTVPLEFKKCCYG 584

  Fly   238 ----LIMHTQEILG--FKLHYIWCGTWSV--QDAFGGAIGMLTNESAELCTTPFVPSWNRLHYLH 294
                |:....|.:|  |.|:.:..|.:..  ...:.|.:|.|.:.:|.|..|.|..:..|...:.
Zfish   585 YCIDLLEKLAEDMGFDFDLYIVGDGKYGAYKNGRWTGLVGDLMSGAAHLAVTSFSINSARSQVID 649

  Fly   295 PMTEQAQFRAVCMFRTPHNAGIKAAVFLEPFMPSVWFAFAGLLIFAGVLLWMIFHLERHW----- 354
            ..:.........:.||...|. ....|:.|...|:|     |.||..:.:..:|.....|
Zfish   650 FTSPFFSTSLGILVRTRDTAA-PIGAFMWPLHWSMW-----LGIFVSLHVTAVFLTLYEWKSPFG 708

  Fly   355 -------MQRCLDFIPSLLSSCLISFG-AACIQGSYLMPKSAGGRLAFIAVMLTSFLMY--NYYT 409
                   ..|...|..:|.....|.|| .|.|:    .||...||  |:..:...|.::  :.||
Zfish   709 MTPRGRNRDRVFSFSSALNVCYAILFGRTAAIK----PPKCWTGR--FLMNLWAIFCLFCLSTYT 767

  Fly   410 SIVVSTLLGSPVRSNIRTIQ--QLADSSLDVGFDTVPFTKTYLVSSPRPDIRSLYKQKVESKRDP 472
            :.:.:.::|......:..|.  :|...|....|.||      ..||....::..:.:..|..|..
Zfish   768 ANLAAVMVGEKTYEQLSGIHDPKLHHPSQGFRFGTV------RESSAEDYVKKSFPEMHEYMRRY 826

  Fly   473 NSVWLSPEEGVIRVRDQP----GFVYTSEASFMYHFVEKHYLPREISDLNEIILRPESAVYGMVH 533
            |:.  :..:|:..::|.|    .|:........:...:|.|:...::... |.|:..|.
Zfish   827 NAP--TTPDGIDHLKDDPQKLDAFIMDKALLDYWAHADKXYISLLLTGYG-IGLKQNSP------ 882

  Fly   534 LNSTYRQLLTQLQVRMLETGITSKQSRFFSKTKLH------------TFSNSFVIQVGMEYAAPL 586
            |.|...:|::|.           |...|..  .||            :|:.:..:|:|:::.:.|
Zfish   883 LTSNISELVSQY-----------KSDGFMD--MLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGL 934

  Fly   587 FISLLVAYFLALLILILEICWARYAKKKFSTIIPQNQ 623
            |:.|.|...|:||..:.|....|:       :||:.|
Zfish   935 FVMLCVGVALSLLTTLGEHIVHRW-------VIPRMQ 964

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	48/245 (20%)
grin3a	XP_009303361.1	Periplasmic_Binding_Protein_Type_1	36..502	CDD:299141	28/110 (25%)
		ANF_receptor	132..452	CDD:279440	15/56 (27%)
		PBP2_iGluR_NMDA_Nr3	518..908	CDD:270438	84/430 (20%)
		Lig_chan	682..941	CDD:278489	58/297 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591231
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830