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Protein Alignment Ir75c and Gria1

DIOPT Version :9

Sequence 1:	NP_649013.3	Gene:	Ir75c / 39983	FlyBaseID:	FBgn0261401	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_113796.1	Gene:	Gria1 / 50592	RGDID:	621531	Length:	907	Species:	Rattus norvegicus

Alignment Length:	706	Identity:	150/706 - (21%)
Similarity:	263/706 - (37%)	Gaps:	134/706 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YRLIVFNLLEINLSNLMVFHCWS--IKEAFPLVEMLNQNGIFSQYIDVQNPDNLANVHKEYLDSD 69
            ||:: |..||.....|:|..|.|  :......:..|.:|||...||       |||:  .::|.|
  Rat   185 YRML-FQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYI-------LANL--GFMDID 239

  Fly    70 LVRLGVFLDLGCDKA--ELVT-NQSSRARLYNQ----------NLHW--------LLYDEAGNFT 113
            |.:   |.:.|.:..  :||. ..:..||:..|          .:.|        |.||......
  Rat   240 LNK---FKESGANVTGFQLVNYTDTIPARIMQQWRTSDSRDHTRVDWKRPKYTSALTYDGVKVMA 301

  Fly   114 KLTQLFEGANLSL-----------NADVTYVSREDEERFILHDVYNKG-------SHLGGKLNIT 160
            :..|......:.:           |..|.:....|.:| .|..|..:|       :..|.:.|.|
  Rat   302 EAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQR-ALQQVRFEGLTGNVQFNEKGRRTNYT 365

  Fly   161 VDQTLQCNRSHCQVKEYLSE----LHLRPRLQHRMDLSSVTFRLAALVSVL--PINSSEEELLEF 219
            : ..::......:...|.:|    :......|...|.|||..|...:.::|  |....::...:|
  Rat   366 L-HVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQF 429

  Fly   220 LNSDRDSHMDSISRIGNRLIMHTQEILGFKLHYIWCGTWSVQD----AFGGAIGMLTNESAELCT 280
            ..:||  :......:...:..|..  ..::|..:..|.:..:|    |:.|.:|.|....|::..
  Rat   430 EGNDR--YEGYCVELAAEIAKHVG--YSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAV 490

  Fly   281 TPFVPSWNRLHYLHPMTEQAQFRAVCMFRTPHNAGIKAAVFLEPFMPSVWFAFAGLLIFAGVLLW 345
            .|...:..|...:.............|.:.|..:......||:|....:|.......|...|:|:
  Rat   491 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 555

  Fly   346 MI-------FHLERHWMQRCLDFIPS-------LLSSCLISFGAACIQGSYLMPKSAGGRLA--- 393
            ::       :|.|.  .:...|...|       :.:|...|.||...||..:.|:|..||:.
  Rat   556 LVSRFSPYEWHSEE--FEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGV 618

  Fly   394 --FIAVMLTSFLMYNYYTSIVVSTLLGSPVRS--NIRTIQQLADSSLDVGFDTVPFTKTYLVSSP 454
              |..:::.|....|....:.|..:: ||:.|  ::....::|..:|:.|     .||.:.   .
  Rat   619 WWFFTLIIISSYTANLAAFLTVERMV-SPIESAEDLAKQTEIAYGTLEAG-----STKEFF---R 674

  Fly   455 RPDIRSLYKQKVESKRDPNSVWL-SPEEGVIRVRDQPG-FVYTSEASFMYHFVEKHYLPREISDL 517
            |..|....|.....|....||:: :.|||:||||...| :.|..| |.|..::|:    |:..|.
  Rat   675 RSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLE-STMNEYIEQ----RKPCDT 734

  Fly   518 NEIILRPESAVYGM-VHLNSTYRQLLTQLQVRMLETGITSK-QSRFF------------SKTKLH 568
            .::....:|..||: ....|..|..:....:::.|.|:..| :::::            ||.|..
  Rat   735 MKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTS 799

  Fly   569 TFSNSFVIQVGMEYAAPLFISLLVAYFLALLILILEICW-ARYAKKKFS--TIIPQ 621
            ..|.|.|        |.:|..|:....||:|:.::|.|: :|...|:..  .:|||
  Rat   800 ALSLSNV--------AGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQ 847

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.