Protein Alignment Ir75c and gria4a

DIOPT Version :9

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_999971.1
• Gene: gria4a / 407735
• ZFINID: ZDB-GENE-020125-7
• Length: 898
• Species: Danio rerio
• Alignment Length: 515
• Identity: 98/515 - (19%)
• Similarity: 196/515 - (38%)
• Gaps: 85/515 - (16%)

  Fly   152 HLGGKLNITVDQTLQCNRSHCQVKEYLSELHLRPRLQHRMDL---SSVTFRLAALVSVLP----I 209
            |.|.::|.|:| ..:...:..:...|.::|.....:|:.:.:   |::..|...:.:::.    :
Zfish   360 HYGRRVNYTMD-VFELKSNGPRKIGYWNDLDKLVLVQNELSMGNDSAMENRTVIVTTIMEGPYVM 423

  Fly   210 NSSEEELLEFLNSDRDSHMDSISRIGNRLIMHTQEILGFKLHYIWCGTWSVQD----AFGGAIGM 270
            .....|:.|.........:|..|.:...:      .:.:|:..:..|.:..:|    .:.|.:|.
Zfish   424 LKKNWEMYEGNEQFEGYCVDLASEVAKHI------GIKYKISIVLDGKYGARDPETKIWNGMVGE 482

  Fly   271 LTNESAELCTTPFVPSWNRLHYLHPMTEQAQFRAVCMFRTPHNAGIKAAVFLEPFMPSVWFAFAG 335
            |....||:...|...:..|...:.............|.:.|..:......||:|....:|.....
Zfish   483 LVYGKAEIAVAPLAITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVF 547

  Fly   336 LLIFAGVLLWMI-------FHLERHWMQRCLDFIPS--------LLSSCLISFGAACIQGSYLMP 385
            ..|...|:|:::       :|.|.  .:...|..||        :.:|...|.||...||....|
Zfish   548 AYIGVSVVLFLVSRFSPYEWHTEE--PEEGSDGPPSDQPPNEFGIFNSLWFSLGAFMQQGCDFTP 610

  Fly   386 KSAGGRLA-----FIAVMLTSFLMYNYYTSIVVSTLLGSPVRS--NIRTIQQLADSSLDVGFDTV 443
            :|..||:.     |..:::.|....|....:.|..:: ||:.|  ::....::|..:||.|....
Zfish   611 RSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV-SPIESAEDLAKQTEIAYGTLDSGSTKE 674

  Fly   444 PFTKTYLVSSPRPDIRSLYKQ--KVESKRDPNSVWLSPEEGVIRVRDQPG-FVYTSEASFMYHFV 505
            .|.::.:         ::|::  ......:|.....:..|||.|||...| :.:..| |.|..:.
Zfish   675 FFRRSKI---------AVYEKMWSYMKSAEPTVFTKTTAEGVARVRKSKGKYAFLLE-STMNEYT 729

  Fly   506 EKHYLPREISDLNEIILRPESAVYGMVHLNSTYRQLLTQLQVRML---ETGITSK-QSRFF---- 562
            |:    |:..|..::....:|..||:.....:  ||.|.:.:.:|   |.|:..| :::::
Zfish   730 EQ----RKPCDTMKVGGNLDSKGYGVATPKGS--QLGTPVNLAVLKLSEAGVLDKLKNKWWYDKG 788

  Fly   563 --------SKTKLHTFSNSFVIQVGMEYAAPLFISLLVAYFLALLILILEICWARYAKKK 614
                    ||.|...       .:.:...|.:|..|:....||:|:.::|.|:...|:.|
Zfish   789 ECGPKDSGSKDKSSQ-------ALSLSNVAGVFYILVGGLGLAMLVALVEFCYKSRAEAK 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	54/252 (21%)
gria4a	NP_999971.1	PBP1_iGluR_AMPA_GluR4	23..393	CDD:107383	7/33 (21%)
		ANF_receptor	34..375	CDD:279440	5/15 (33%)
		PBP2_iGluR_AMPA_GluR4	408..790	CDD:270445	76/406 (19%)
		Lig_chan	540..821	CDD:278489	62/306 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591221
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940