Protein Alignment Ir75c and gria1b

DIOPT Version :10

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_991293.1
• Gene: gria1b / 403044
• ZFINID: ZDB-GENE-020125-2
• Length: 917
• Species: Danio rerio
• Alignment Length: 720
• Identity: 137/720 - (19%)
• Similarity: 253/720 - (35%)
• Gaps: 191/720 - (26%)

  Fly    52 VQNPDNLANVHKEY---LDSDLVRLGVFLDL-GCDKAELVTNQSSRARLYNQNLHWLLYDEAGNF 112
            :|:.||    .||:   ||.:|.||...|:| ...|..|            :|.|::|.:.....
Zfish   188 IQDLDN----KKEFKIILDCELERLNSILNLIAAQKKNL------------KNYHYILANLGFLD 236

  Fly   113 TKLTQLFE-GANLS----LNADVTYVSR--EDEERFILHDVYNKGSHL--GGKL---NITV---- 161
            ..||:..: |||::    :|.....|||  :|...|...|:.:....|  .|.|   .:||
Zfish   237 LNLTEFRKGGANVTGFQLMNYTNPTVSRTIQDWLEFDSKDLKSPKRRLKYTGALTYDGVTVMATA 301

  Fly   162 ---------DQTLQCNRSHC------------QVKEYLSELHLRPRLQHRMDLSSVTFRLAALVS 205
                     |.:.:.|...|            .::..|.::.......| :..:....|....||
Zfish   302 FQNLRKQRIDISRRGNAGECLANPPAPWGQGIDIQRALQQVQFEGLTGH-VQFNDKGHRTNFTVS 365

  Fly   206 VLPINSSEEELLEFLNSDRDSHMDSIS---------RIGNRLIMHT--------------QEILG 247
            |:....|..:.:.:.| .|:.::.:.:         .:.||..:.|              ::::|
Zfish   366 VMEFGPSGPKKVGYWN-QREKYVSTATYSNMLNETFGLQNRTYVVTTILEAPYVMLKKNHEQLVG 429

  Fly   248 ----------------------FKLHYIWCGTWSVQDA----FGGAIGMLTNESAELCTTPFVPS 286
                                  ::|..:..|.:..:||    :.|.:|.|....|::...|...:
Zfish   430 NDKYEGYCVELAAEIAKHVGYSYRLELVGDGKYGARDAETMMWNGMVGELVYGKADVAVAPLTIT 494

  Fly   287 WNRLHYLHPMTEQAQFRAVCMFRTPHNAGIKAAVFLEPFMPSVWFAFAGLLIFAGVLLWMIFHLE 351
            ..|...:.............|.:.|..:......||:|....:|.......|...|:|:::....
Zfish   495 LVREEVIDFSKPFMSLGISIMIKKPTKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFS 559

  Fly   352 RH-WM---------QRCLDFIPS-----------------------------LLSSCLISFGAAC 377
            .: |.         |:..:..||                             :.:|...|.||..
Zfish   560 PYEWHADDEEETADQQNQNQPPSPEPNQSPNQSQNQREEKQEKQPEHTNEFGIFNSLWFSLGAFM 624

  Fly   378 IQGSYLMPKSAGGRLA-----FIAVMLTSFLMYNYYTSIVVSTLLGSPVRS--NIRTIQQLADSS 435
            .||..:.|:|..||:.     |..:::.|....|....:.|..:: ||:.|  ::....::|..:
Zfish   625 QQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV-SPIESAEDLAKQTEIAYGT 688

  Fly   436 LDVGFDTVPFTKTYLVSSPRPDIRSLYKQKVESKRDPNSVWLSPEEGVIRVRDQPG-FVYTSEAS 499
            ||.|     .||.:...|.......::...  ...:|.....:.:|||:|||...| :.|..| |
Zfish   689 LDGG-----STKEFFRRSKIAVFEKMWSYM--KSAEPTVFVKTTDEGVVRVRKSKGKYAYLLE-S 745

  Fly   500 FMYHFVEKHYLPREISDLNEIILRPESAVYGM-VHLNSTYRQLLTQLQVRMLETGITSK-QSRFF 562
            .|..::|:    |:..|..::....:|..||: ....|..|..:....:::.|.|:..| :::::
Zfish   746 TMNEYIEQ----RKPCDTMKVGGNLDSKGYGVATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWW 806

  Fly   563 ------------SKTKLHTFSNSFVIQVGMEYAAPLFISLLVAYFLALLILILEICW-ARYAKKK 614
                        ||.|....|.|.|        |.:|..|:....||:|:.::|.|: :|...::
Zfish   807 YDKGECGSGGGDSKDKTSALSLSNV--------AGVFYILIGGLGLAMLVALVEFCYKSRIESRR 863

  Fly   615 FSTII 619
            ...||
Zfish   864 MKQII 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..>508	CDD:459656	45/226 (20%)
gria1b	NP_991293.1	PBP1_iGluR_AMPA_GluR1	26..390	CDD:380613	46/219 (21%)
		PBP2_iGluR_AMPA_GluR1	404..812	CDD:270447	74/420 (18%)