Protein Alignment Ir75c and gria3b

DIOPT Version :9

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_938174.1
• Gene: gria3b / 368416
• ZFINID: ZDB-GENE-030616-53
• Length: 883
• Species: Danio rerio
• Alignment Length: 670
• Identity: 125/670 - (18%)
• Similarity: 241/670 - (35%)
• Gaps: 120/670 - (17%)

  Fly     7 YRLIVFNLLEINLSNLMVFHCWSIKEAFPLVEMLNQNGIFSQYIDVQNPDNL--------ANVHK 63
            |..|:.||...|:|...||...:....|.::.  .:|.:..|::  |..|.|        .|...
Zfish   233 YHYIIANLGFTNISLDKVFLGGANISGFQIIN--PENLVVQQFL--QRWDRLDEREFPEAKNTPL 293

  Fly    64 EY-----LDSDLVRLGVFLDLGCDKAELVTNQSSRARLYNQNLHWLLYDEAGNFTKLTQLFEGAN 123
            :|     .|:.||....|..|...:.::....|:...|.|..:.|....:.....|:.|: :|..
Zfish   294 KYTSALSYDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQV-QGMT 357

  Fly   124 LSLNADVTYVSREDEERFILHDVYNKGSHLGGKLNITVDQTLQCNRSHCQVKEYLSELHLRPRL- 187
            .::..|                      ..|.:.|.|:| ..:......:...|.:|......:
Zfish   358 GNIQFD----------------------SFGRRTNYTID-VYEMKTGGPRKIGYWNEFERFVNIM 399

  Fly   188 --QHRMDLSSVTFRLAALVSVLPINSSEEELLEFLNSDRDSHMDSISRIGNRLIMHTQEI----- 245
              |...|.|||..|...:.:::       |....:......|::...:.....:....||
Zfish   400 DQQFTNDSSSVENRTIVVTTIM-------EAPYVMYKKNHMHLEGNEKYEGYCVDLASEIAKHVG 457

  Fly   246 LGFKLHYIWCGTWSVQD----AFGGAIGMLTNESAELCTTPFVPSWNRLHYLHPMTEQAQFRAVC 306
            :.::|..:..|.:..:|    ::.|.:|.|....|::...|...:..|...:.............
Zfish   458 IKYRLSIVMDGKYGARDPETKSWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISI 522

  Fly   307 MFRTPHNAGIKAAVFLEPFMPSVWFAFAGLLIFAGVLLWMIFHLERH-WMQRCLDFIP------- 363
            |.:.|..:......||:|....:|.......|...|:|:::.....: |.....|.:.
Zfish   523 MIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWQLDETDEVKDPQTPPD 587

  Fly   364 -----SLLSSCLISFGAACIQGSYLMPKSAGGRLA-----FIAVMLTSFLMYNYYTSIVVSTLLG 418
                 .:.:|...|.||...||..:.|:|..||:.     |..:::.|....|....:.|..::
Zfish   588 PPNDFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV- 651

  Fly   419 SPVRS--NIRTIQQLADSSLDVGFDTVPFTKTYLVSSPRPDIRSLYKQ--KVESKRDPNSVWLSP 479
            ||:.|  ::....::|..:||.|.....|.::.:         ::|::  ......:|:....:.
Zfish   652 SPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKI---------AVYEKMWSYMKSAEPSVFAKTT 707

  Fly   480 EEGVIRVRDQPG-FVYTSEASFMYHFVEKHYLPREISDLNEIILRPESAVYGM-VHLNSTYRQLL 542
            .:||.|||...| |.:..| |.|..::|:    |:..|..::....:|..||: ....|..|..:
Zfish   708 PDGVARVRKSKGKFAFLLE-STMNEYIEQ----RKPCDTMKVGGNLDSKGYGVATPKGSALRNAV 767

  Fly   543 TQLQVRMLETGITSK-QSRFF------------SKTKLHTFSNSFVIQVGMEYAAPLFISLLVAY 594
            ....:::.|.|:..| :::::            ||.|....|.|.|        |.:|..|:...
Zfish   768 NLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNV--------AGVFYILVGGL 824

  Fly   595 FLALLILILEICWARYAKKK 614
            .||:::.::|.|:...|:.|
Zfish   825 GLAMMVALIEFCYKSRAEAK 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	49/248 (20%)
gria3b	NP_938174.1	Periplasmic_Binding_Protein_Type_1	25..396	CDD:299141	35/190 (18%)
		ANF_receptor	36..379	CDD:279440	33/173 (19%)
		PBP2_iGluR_AMPA	412..794	CDD:270433	70/403 (17%)
		Lig_chan	544..824	CDD:278489	60/302 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591262
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840