Protein Alignment Ir75c and clumsy

DIOPT Version :9

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Alignment Length: 739
• Identity: 152/739 - (20%)
• Similarity: 264/739 - (35%)
• Gaps: 245/739 - (33%)

  Fly    14 LLEINLS--NLMVFHCWSIKEAFPLVEMLNQNGIFSQYIDVQNPDNLANVHKEYLDSDLVRLG-- 74
            |.||.||  |.::.||                          .||||..:.::  .::|..||
  Fly   199 LKEIKLSTDNCLILHC--------------------------APDNLLKILQQ--ANELKMLGEY 235

  Fly    75 --VFLDL----GCDKAEL--VTNQSSRARLYN-QNLHW--LLYD------EAGNFTKLTQLFEGA 122
              ||:.|    ..|..||  |....:..||.: .:.|.  :::|      ..|.:.|:..
  Fly   236 QSVFIPLLDTHSIDFGELSGVEANITTVRLMDPSDFHVKNVVHDWEEREKREGRYFKVDP----- 295

  Fly   123 NLSLNADVTYVSREDEERFILHD---VYNKG-SHLGGKLNITVDQTLQCNRSH-----CQVKEYL 178
                       :|...:..:|:|   :::|| :.||....:|... |:|.|..     .::.|::
  Fly   296 -----------NRVKSQMILLNDAVWLFSKGLTELGIFEELTAPD-LECRRKKPWPFGKRIIEFI 348

  Fly   179 ---SELHLRPRLQHR------------MDLSSVTFRLAALVSVLPINSSEEELLEFLNSDRDSHM 228
               ||.....|:...            |:|:|..|  ..|.:..|:|.     |:.||.|.:|..
  Fly   349 KARSEETSTGRIDFNENGQRSFFTLRFMELNSDGF--LDLATWDPVNG-----LDVLNDDEESEK 406

  Fly   229 DSISRIGNR------------------------------------LIMHTQEILGFKLHYIWC-- 255
            ....::.|:                                    ||....::|.||..:...
  Fly   407 RVGQKLSNKTFIVSSRLGAPFLTLREPQEGEILTGNSRYEGYSIDLINEIAKMLNFKFEFRMSPD 471

  Fly   256 GTW----SVQDAFGGAIGMLTNESAEL--C--------------TTPFVPSWNRLHYLHPMTEQA 300
            |.:    .|...:.|.:..|.:.:|:|  |              |.||:.....:.:..|.|...
  Fly   472 GKYGALNKVTQTWDGIVRQLIDGNADLGICDLTMTSSRRQAVDFTPPFMTLGISILFSKPPTPPT 536

  Fly   301 QFRAVCMFRTPHNAGIKAAVFLEPFMPSVW------FAFAGLLIFAGVLL----WMIFH------ 349
            ...:                ||.||...||      :.|..||:||...:    |...|
  Fly   537 DLFS----------------FLSPFSLDVWIYMGSAYLFISLLLFALARMAPDDWENPHPCKEPE 585

  Fly   350 -LERHWMQRCLDFIPSLLSSCLISFGAACIQGSYLMPKSAGGRLA-----FIAVMLTSFLMYNYY 408
             :|..|         |::::..:|.|:...||..::||:|..||.     |.|:|     |.|.|
  Fly   586 EVENIW---------SIMNTTWLSIGSLMGQGCDILPKAASTRLVTGMWWFFALM-----MLNSY 636

  Fly   409 TSIVVSTLLGSPVRSNIRTIQQLADSS-----LDVGFDTVPFTKTYLVSSPRPDIRSLYKQ---K 465
            |:.:.:.|..|...::|.:.:.||..|     ...|..|:.|.        |....|.|::   .
  Fly   637 TANLAAFLTNSRQANSINSAEDLAAQSKIKYGAMAGGSTMGFF--------RDSNFSTYQKMWTA 693

  Fly   466 VESKRDPNSVWLSPEEGVIRVRDQPG---FVYTSEASFMYHFVEKHYLPREISDLNEIILRPESA 527
            :|| ..|:....:.:|||.||  |.|   :.:..|::.:.:.||:.      .||.:|....:..
  Fly   694 MES-ASPSVFTKTNDEGVERV--QKGKNLYAFLMESTTLEYNVERK------CDLVQIGGWLDYK 749

  Fly   528 VYGM-VHLNSTYRQLLTQLQVRMLETGITSKQSRFFSKTKLHTFSN--------SFVIQVGMEYA 583
            .||: :..||.||:.::...:::.|.|..::..|.:.| ::|...|        ....::|:|..
  Fly   750 SYGIAMPFNSPYRKQISAAVLKLGELGQLAELKRKWWK-EMHGGGNCEKSDEDGGDTPELGLENV 813

  Fly   584 APLFISLLVAYFLALLILILEICW 607
            ..:|:.|.:....|:::...|..|
  Fly   814 GGVFLVLGLGLLSAMVLGCTEFLW 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	63/258 (24%)
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	26..396	CDD:107377	50/248 (20%)
		ANF_receptor	39..379	CDD:279440	44/224 (20%)
		PBP2_iGluR_Kainate	414..787	CDD:270432	87/419 (21%)
		Lig_chan	548..812	CDD:278489	69/295 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462589
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840