Protein Alignment Ir75c and Ir25a

DIOPT Version :9

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Alignment Length: 753
• Identity: 142/753 - (18%)
• Similarity: 240/753 - (31%)
• Gaps: 282/753 - (37%)

  Fly    29 SIKEAFPLVEMLNQNGIFSQYIDVQNPDNLAN-------------VHKEYLDSDLVRLGV----- 75
            |:|.|:     ..:|  |:.:...||...:::             .:.:|.|    |||:
  Fly   249 SVKPAY-----FERN--FAWHAITQNEGEISSQRDNATIMFMKPMAYTQYRD----RLGLLRTTY 302

  Fly    76 ------------FLDLGCDKAELVTNQSSRARLYNQNLHWLLYDEAGNFTKLTQLFEGANL-SLN 127
                        :.||.. ::.|...:..::..:.:::.:|..|:          |:|.|. ..|
  Fly   303 NLNEEPQLSSAFYFDLAL-RSFLTIKEMLQSGAWPKDMEYLNCDD----------FQGGNTPQRN 356

  Fly   128 ADVTYVSREDEERFILHDVYNKGSHLGGKLNIT----------VDQTLQCNRSHCQVKEYLSELH 182
            .|             |.|.:.|         ||          |.|:.|....|..:|
  Fly   357 LD-------------LRDYFTK---------ITEPTSYGTFDLVTQSTQPFNGHSFMK------- 392

  Fly   183 LRPRLQHRMDLSSVTFRLAALVS-------VLPINS----SEEELLEFLNSD------------- 223
                  ..||::.:..|..:.|:       :..:||    .:||.::.|.:|
  Fly   393 ------FEMDINVLQIRGGSSVNSKSIGKWISGLNSELIVKDEEQMKNLTADTVYRIFTVVQAPF 451

  Fly   224 --RDSH---------MDSISRIGNRLIMH----TQEILGFKLHYIWCGTWSVQDAFGGAIGMLTN 273
              ||..         :|.|:.|.  .|:|    .||:...|.     |.......:.|.:..|.:
  Fly   452 IMRDETAPKGYKGYCIDLINEIA--AIVHFDYTIQEVEDGKF-----GNMDENGQWNGIVKKLMD 509

  Fly   274 ESAELCTTPFVPSWNRLHYLHPMTEQAQFRAVCMFRTPHNAGIKAAVFLE-PFMPS--------- 328
            :.|::             .|..|:..|:...|..|..|:...:...:.:: |..||
  Fly   510 KQADI-------------GLGSMSVMAEREIVIDFTVPYYDLVGITIMMQRPSSPSSLFKFLTVL 561

  Fly   329 ---VWFAFAGLLIFAGVLLWMIFHLERHW----------------------MQRCLDFIPSLLSS 368
               ||........|...|:| ||.   .|                      ::.||.|
  Fly   562 ETNVWLCILAAYFFTSFLMW-IFD---RWSPYSYQNNREKYKDDEEKREFNLKECLWF------- 615

  Fly   369 CLISFGAACIQGSYLMPKSAGGRLAFIAVMLTSFLMYNYYTSIVVSTL----LGSPVRS------ 423
            |:.|...   ||....||:..|||......|..|::...||:.:.:.|    |.:||.|
  Fly   616 CMTSLTP---QGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVESLDDLAK 677

  Fly   424 -------------------NIRTIQQL-----ADSSLDVGFDTVPFTKTYLVSSPRPDIRSLYKQ 464
                               .:..|:|:     .|.||:.....|..:|..:...|..|..:...|
  Fly   678 QYKILYAPLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSDKYTKMWQ 742

  Fly   465 KVESKRDPNSVWLSPEEGVIRVRDQ---PGFVYTSEASFMYHFVEKHYLPREISDL----NEIIL 522
            .::..:.|.::    :|.|.|||:.   .||.:..:|:      :..||.....||    .|...
  Fly   743 AMQEAKLPATL----DEAVARVRNSTAATGFAFLGDAT------DIRYLQLTNCDLQVVGEEFSR 797

  Fly   523 RPES-AVYGMVHLNSTYRQ-LLTQLQVRMLETGITSKQSRFFSKTKLHTFSNSFVIQ-------- 577
            :|.: ||....||...:.. :||.|..|.||            |.|...:.|...:.
  Fly   798 KPYAIAVQQGSHLKDQFNNAILTLLNKRQLE------------KLKEKWWKNDEALAKCDKPEDQ 850

  Fly   578 ---VGMEYAAPLFISLLVAYFLALLILILEICWARYAK 612
               :.::....:||.:.|...:|.:.|:.|..|.||.|
  Fly   851 SDGISIQNIGGVFIVIFVGIGMACITLVFEYWWYRYRK 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	65/301 (22%)
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	40..426	CDD:107378	38/233 (16%)
		PBP2_iGluR_putative	438..836	CDD:270435	90/453 (20%)
		Lig_chan	565..870	CDD:278489	70/340 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462808
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840