Protein Alignment Ir75c and GluRIIC

DIOPT Version :10

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Alignment Length: 731
• Identity: 130/731 - (17%)
• Similarity: 241/731 - (32%)
• Gaps: 245/731 - (33%)

  Fly    23 MVFHCWSIKEAFPLVEMLNQN---GIFSQYIDVQNPDNLANV--HKEYLDSDLVRLGVFLDLGCD 82
            :|..|    |...|||:||.:   |:..||    |...|.|:  :.::|:          :|..|
  Fly   213 VVLDC----EPNMLVELLNSSTEFGLTGQY----NHIFLTNLETYTDHLE----------ELAAD 259

  Fly    83 KAELVTNQSSRARLYNQN--LHWLLYDEAGNFTKLTQLFEGANLSLNADVTYVSREDEERFILHD 145
            ......|.::...|.|.:  .:.|.|   |..|:            ..::.|.| .|..|.::||
  Fly   260 NETFAVNITAARLLVNPDPPPYSLPY---GYVTQ------------RDNIVYES-SDPPRTLIHD 308

  Fly   146 VYNKGSHLGGKL---------------NITVDQTLQCNRSHCQVKEYLSELHLRPRLQHRMDLSS 195
            :.:....|..:.               .||.|......|:.. :..||:.|     ::....:::
  Fly   309 LIHDALQLFAQSWRNASFFYPDRMVVPRITCDFAASGGRTWA-MGRYLARL-----MKGTSGVNN 367

  Fly   196 VTFRLAALVSVLPINSSEEEL-----------------------LEFLNSDRDSHMDSISRIGNR 237
            ..||    .|:|..:...:.:                       :..||.|..:....|.|:..|
  Fly   368 TNFR----TSILQFDEDGQRITFNIEVYDPLDGIGIAIWDPRGQITQLNVDVKAQKKMIYRVATR 428

  Fly   238 -----------------------------LIMHTQEILGFKLHYIWCGTWSVQ--------DAFG 265
                                         ||......:||:  |::......|        ..:.
  Fly   429 IGPPYFSYNETARELNLTGNALYQGYAVDLIDAIARHVGFE--YVFVPVADQQYGKLDKETKQWN 491

  Fly   266 GAIGMLTNESAE--LC--------------TTPFVPSWNRLHYLHPMTEQAQFR-AVCMFRTPHN 313
            |.||.:.|..|.  :|              |.||:                |.. ::..:::||.
  Fly   492 GIIGEIINNDAHMGICDLTITQARKTAVDFTVPFM----------------QLGVSILAYKSPHV 540

  Fly   314 AGIKAAVFLEPFMPSVWFAFAGLLIFAGVLL-----------WMIFH--------LERHWMQRCL 359
            .....| :|.||...||. :..:.:|....|           |...|        ||..|
  Fly   541 EKTLDA-YLAPFGGEVWI-WILISVFVMTFLKTIVARISKMDWENPHPCNRDPEVLENQW----- 598

  Fly   360 DFIPSLLSSCLISFGAACIQGSYLMPKSAGGRLAFIAVMLTSFLMYNYYTSIVVSTLLGSPVRSN 424
                .:.::..::..:....|..::|:|...|:......:.:.::.|.||:.:.:.|..|.:..:
  Fly   599 ----RIHNTGWLTVASIMTAGCDILPRSPQVRMFEATWWIFAIIIANSYTANLAAFLTSSKMEGS 659

  Fly   425 IRTIQQLADSSLDVGFDTVPFTKTY--LVSSPRPDIRSLYKQKVESKRDPNSVWLSPEEGVIRVR 487
            |..::.|: :...|.|.|:....||  |..|.....|..:  .:.:..||::......|||.|||
  Fly   660 IANLKDLS-AQKKVKFGTIYGGSTYNLLADSNETVYRLAF--NLMNNDDPSAYTKDNLEGVDRVR 721

  Fly   488 DQPG-FVYTSEASFM-YH-------------FVEKHYLPREISDLNEIILRPESAVYGMVHLNST 537
            ...| :::..|.:.: ||             |.||||                 |:  .|...:.
  Fly   722 KNRGDYMFLMETTTLEYHREQNCDLRSVGEKFGEKHY-----------------AI--AVPFGAE 767

  Fly   538 YRQLLTQLQVRMLETG-ITSKQSRFFSKTKLHTFSN---------SFVIQVGMEYAAPLFISLLV 592
            ||..|:...:::.|.| :...:.:::.......|..         :|....|:.|.  |:..:|:
  Fly   768 YRSNLSVAILKLSERGELYDLKQKWWKNPNASCFEEPDPDATPDMTFEELRGIFYT--LYAGILI 830

  Fly   593 AYFLAL---LILILEI 605
            |:.:.:   |:.:.::
  Fly   831 AFLIGITEFLVYVQQV 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..>508	CDD:459656	42/215 (20%)
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	42/239 (18%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	76/421 (18%)
		Lig_chan	554..827	CDD:459656	57/306 (19%)