Protein Alignment Ir75c and Gria4

DIOPT Version :10

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_058959.2
• Gene: Gria4 / 29629
• RGDID: 61863
• Length: 902
• Species: Rattus norvegicus
• Alignment Length: 511
• Identity: 101/511 - (19%)
• Similarity: 200/511 - (39%)
• Gaps: 78/511 - (15%)

  Fly   152 HLGGKLNITVDQTLQCNRSHCQVKEYLSELHLRPRLQHR----MDLSSVTFRLAALVSVLP---- 208
            |.|.::|.|:| ..:...:..:...|.:::.....:|..    .|.:::..|...:.:::.
  Rat   365 HYGRRVNYTMD-VFELKSTGPRKVGYWNDMDKLVLIQDMPTLGNDTAAIENRTVVVTTIMESPYV 428

  Fly   209 INSSEEELLEFLNSDRDSHMDSISRIGNRLIMHTQEILGFKLHYIWCGTWSVQDA----FGGAIG 269
            :.....|:.|..:......:|..|.|...:      .:.:|:..:..|.:..:||    :.|.:|
  Rat   429 MYKKNHEMFEGNDKYEGYCVDLASEIAKHI------GIKYKIAIVPDGKYGARDADTKIWNGMVG 487

  Fly   270 MLTNESAELCTTPFVPSWNRLHYLHPMTEQAQFRAVCMFRTPHNAGIKAAVFLEPFMPSVWFAFA 334
            .|....||:...|...:..|...:.............|.:.|..:......||:|....:|....
  Rat   488 ELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIV 552

  Fly   335 GLLIFAGVLLWMI-------FHLE--RHWMQRCLDFIPS---LLSSCLISFGAACIQGSYLMPKS 387
            ...|...|:|:::       :|.|  ....:...|..|:   :.:|...|.||...||..:.|:|
  Rat   553 FAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRS 617

  Fly   388 AGGRLA-----FIAVMLTSFLMYNYYTSIVVSTLLGSPVRS--NIRTIQQLADSSLDVGFDTVPF 445
            ..||:.     |..:::.|....|....:.|..:: ||:.|  ::....::|..:||.|.....|
  Rat   618 LSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV-SPIESAEDLAKQTEIAYGTLDSGSTKEFF 681

  Fly   446 TKTYLVSSPRPDIRSLYKQKVESKR--DPNSVWLSPEEGVIRVRDQPG-FVYTSEASFMYHFVEK 507
            .::.:         ::|::.....|  :|:....:..|||.|||...| |.:..| |.|..::|:
  Rat   682 RRSKI---------AVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLE-STMNEYIEQ 736

  Fly   508 HYLPREISDLNEIILRPESAVYGM-VHLNSTYRQLLTQLQVRMLETGITSK-QSRFF-------- 562
                |:..|..::....:|..||: ....|:.|..:....:::.|.|:..| :::::
  Rat   737 ----RKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGP 797

  Fly   563 ----SKTKLHTFSNSFVIQVGMEYAAPLFISLLVAYFLALLILILEICWARYAKKK 614
                ||.|....|.|.|        |.:|..|:....||:|:.::|.|:...|:.|
  Rat   798 KDSGSKDKTSALSLSNV--------AGVFYILVGGLGLAMLVALIEFCYKSRAEAK 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..>508	CDD:459656	45/201 (22%)
Gria4	NP_058959.2	PBP1_iGluR_AMPA_GluR4	28..400	CDD:380611	6/35 (17%)
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	77/401 (19%)