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Protein Alignment Ir75c and Gria2

DIOPT Version :9

Sequence 1:	NP_649013.3	Gene:	Ir75c / 39983	FlyBaseID:	FBgn0261401	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_001077280.1	Gene:	Gria2 / 29627	RGDID:	61862	Length:	883	Species:	Rattus norvegicus

Alignment Length:	720	Identity:	140/720 - (19%)
Similarity:	257/720 - (35%)	Gaps:	195/720 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 NPDNLANVHKE------YLDSDLVR-LGVFLDLGCDKAELVTNQSSRARLYNQNLHWLLYD---E 108
            |..|:.|..|:      :.|.:|.: ..|.||...||...:.:|......:.:..|:::.:   .
  Rat   179 NVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFT 243

  Fly   109 AGNFTKLTQLFEGANLS----LNADVTYVSREDEERFILHDVYNKGSHLGGKLNITVDQTLQCNR 169
            .|:..|:.  |.|||:|    ::.|.:.||:..|....|.:....|:|     ..|:..|.....
  Rat   244 DGDLLKIQ--FGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAH-----TATIKYTSALTY 301

  Fly   170 SHCQVKEYLSELHLRPRLQHRMDLS------------------------------------SVTF 198
            ...||   ::|.....|.| |:::|                                    ::.|
  Rat   302 DAVQV---MTEAFRNLRKQ-RIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKF 362

  Fly   199 -----RLAALVSVLPINS---------SEEELLEFLNSDRDSHMDSISRIGNRLIMHT------- 242
                 |:...::::.:.:         ||.:.:....::..|..|: |.:.|:.::.|
  Rat   363 DQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDT-SGLENKTVVVTTILESPY 426

  Fly   243 ------QEIL---------------------GF--KLHYIWCGTWSVQDA----FGGAIGMLTNE 274
                  .|:|                     ||  ||..:..|.:..:||    :.|.:|.|...
  Rat   427 VMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYG 491

  Fly   275 SAELCTTPFVPSWNRLHYLHPMTEQAQFRAVCMFRTPHNAGIKAAVFLEPFMPSVWFAFAGLLIF 339
            .|::...|...:..|...:.............|.:.|..:......||:|....:|.......|.
  Rat   492 KADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIG 556

  Fly   340 AGVLLWMI-------FHLERHWMQRCLDFIPS-----LLSSCLISFGAACIQGSYLMPKSAGGRL 392
            ..|:|:::       :|.|.....|......|     :.:|...|.||...||..:.|:|..||:
  Rat   557 VSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRI 621

  Fly   393 A-----FIAVMLTSFLMYNYYTSIVVSTLLGSPVRS--NIRTIQQLADSSLDVGFDTVPFTK--- 447
            .     |..:::.|....|....:.|..:: ||:.|  ::....::|..:||.| .|..|.:
  Rat   622 VGGVWWFFTLIIISSYTANLAAFLTVERMV-SPIESAEDLSKQTEIAYGTLDSG-STKEFFRRSK 684

  Fly   448 --------TYLVSSPRPDIRSLYKQKVESKRDPNSVWLSPEEGVIRVRDQPG-FVYTSEASFMYH 503
                    ||:.|:                 :|:....:..|||.|||...| :.|..| |.|..
  Rat   685 IAVFDKMWTYMRSA-----------------EPSVFVRTTAEGVARVRKSKGKYAYLLE-STMNE 731

  Fly   504 FVEKHYLPREISDLNEIILRPESAVYGM-VHLNSTYRQLLTQLQVRMLETGITSK-QSRFF---- 562
            ::|:    |:..|..::....:|..||: ....|:....:....:::.|.|:..| :::::
  Rat   732 YIEQ----RKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKG 792

  Fly   563 --------SKTKLHTFSNSFVIQVGMEYAAPLFISLLVAYFLALLILILEICWARYAKKKFSTII 619
                    ||.|....|.|.|        |.:|..|:....||:|:.::|.|:...|:.|...:.
  Rat   793 ECGSGGGDSKEKTSALSLSNV--------AGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVA 849

  Fly   620 --PQN 622
              |||
  Rat   850 KNPQN 854

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.