Protein Alignment Ir75c and GRIN2A

DIOPT Version :9

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_016878661.1
• Gene: GRIN2A / 2903
• HGNCID: 4585
• Length: 1516
• Species: Homo sapiens
• Alignment Length: 495
• Identity: 102/495 - (20%)
• Similarity: 166/495 - (33%)
• Gaps: 140/495 - (28%)

  Fly    47 SQYIDVQNPDNLANVHKEYLDSDL---VRLGVFLDLGCDKAELVTNQSS-----------RARLY 97
            ::.|..:.|..|.:|..:..|..|   ||.|:.:        |.|..||           :|..|
Human   317 TELIPKEFPSGLISVSYDDWDYSLEARVRDGIGI--------LTTAASSMLEKFSYIPEAKASCY 373

  Fly    98 NQ---------NLHWLLYDEAGNFTKLTQLFEGANLSLNADVTYVSREDEERFILHD-----VYN 148
            .|         .||..:.    |.|     ::|.:||..          ||.:.:|.     |.|
Human   374 GQMERPEVPMHTLHPFMV----NVT-----WDGKDLSFT----------EEGYQVHPRLVVIVLN 419

  Fly   149 KGSHLGGKLNITVDQTLQCNRSHCQVKEYLSELHLRPRLQHRMDLSSVTFRLAALVSV------- 206
            |... ..|:....:.||...  |.....|.|.....|...|   ||.||...|..|.|
Human   420 KDRE-WEKVGKWENHTLSLR--HAVWPRYKSFSDCEPDDNH---LSIVTLEEAPFVIVEDIDPLT 478

  Fly   207 -------------LPINSSEEELLEFLNSDRDSHMDSISRIGNRLIMHTQEIL-------GFKLH 251
                         :.||:|..|.:......:...:|.:.:: :|.:..|.::.       |.|::
Human   479 ETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKL-SRTVKFTYDLYLVTNGKHGKKVN 542

  Fly   252 YIWCGTWS--VQDAFGGAIGMLT--NESAELC--TTPFVPSWNRLHYLHPMTEQAQFRAVCMFRT 310
            .:|.|...  |......|:|.||  .|.:|:.  :.|||.:                 .:.:..:
Human   543 NVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVET-----------------GISVMVS 590

  Fly   311 PHNAGIKAAVFLEPFMPSVW-FAFAGLLIFAGVLLWMIFHL-----ERHWMQRCLDFIPSL---- 365
            ..|..:..:.|||||..||| ..|..|||.:.:.:::..:.     .|:..:......||.
Human   591 RSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGK 655

  Fly   366 ---LSSCLISFGAACIQGSYLMPKSAGGRL-----AFIAVMLTSFLMYNYYTSIVVSTLLGSPVR 422
               |...|:...:..:|.    ||....::     ||.||:..:....|....::....:.....
Human   656 AIWLLWGLVFNNSVPVQN----PKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTG 716

  Fly   423 SNIRTIQQLADSSLDVGFDTVPFTKTYLVSSPRPDIRSLY 462
            .:.:..|:..|.|....|.|||      ..|...:||:.|
Human   717 LSDKKFQRPHDYSPPFRFGTVP------NGSTERNIRNNY 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	31/153 (20%)
GRIN2A	XP_016878661.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155897
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740