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Protein Alignment Ir75c and GRIA4

DIOPT Version :9

Sequence 1:	NP_649013.3	Gene:	Ir75c / 39983	FlyBaseID:	FBgn0261401	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_000820.4	Gene:	GRIA4 / 2893	HGNCID:	4574	Length:	902	Species:	Homo sapiens

Alignment Length:	511	Identity:	101/511 - (19%)
Similarity:	200/511 - (39%)	Gaps:	78/511 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 HLGGKLNITVDQTLQCNRSHCQVKEYLSELHLRPRLQH----RMDLSSVTFRLAALVSVLP---- 208
            |.|.::|.|:| ..:...:..:...|.:::.....:|.    ..|.:::..|...:.:::.
Human   365 HYGRRVNYTMD-VFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMESPYV 428

  Fly   209 INSSEEELLEFLNSDRDSHMDSISRIGNRLIMHTQEILGFKLHYIWCGTWSVQDA----FGGAIG 269
            :.....|:.|..:......:|..|.|...:      .:.:|:..:..|.:..:||    :.|.:|
Human   429 MYKKNHEMFEGNDKYEGYCVDLASEIAKHI------GIKYKIAIVPDGKYGARDADTKIWNGMVG 487

  Fly   270 MLTNESAELCTTPFVPSWNRLHYLHPMTEQAQFRAVCMFRTPHNAGIKAAVFLEPFMPSVWFAFA 334
            .|....||:...|...:..|...:.............|.:.|..:......||:|....:|....
Human   488 ELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIV 552

  Fly   335 GLLIFAGVLLWMI-------FHLE--RHWMQRCLDFIPS---LLSSCLISFGAACIQGSYLMPKS 387
            ...|...|:|:::       :|.|  ....:...|..|:   :.:|...|.||...||..:.|:|
Human   553 FAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRS 617

  Fly   388 AGGRLA-----FIAVMLTSFLMYNYYTSIVVSTLLGSPVRS--NIRTIQQLADSSLDVGFDTVPF 445
            ..||:.     |..:::.|....|....:.|..:: ||:.|  ::....::|..:||.|.....|
Human   618 LSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV-SPIESAEDLAKQTEIAYGTLDSGSTKEFF 681

  Fly   446 TKTYLVSSPRPDIRSLYKQKVESKR--DPNSVWLSPEEGVIRVRDQPG-FVYTSEASFMYHFVEK 507
            .::.:         ::|::.....|  :|:....:..|||.|||...| |.:..| |.|..::|:
Human   682 RRSKI---------AVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLE-STMNEYIEQ 736

  Fly   508 HYLPREISDLNEIILRPESAVYGM-VHLNSTYRQLLTQLQVRMLETGITSK-QSRFF-------- 562
                |:..|..::....:|..||: ....|:.|..:....:::.|.|:..| :::::
Human   737 ----RKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGP 797

  Fly   563 ----SKTKLHTFSNSFVIQVGMEYAAPLFISLLVAYFLALLILILEICWARYAKKK 614
                ||.|....|.|.|        |.:|..|:....||:|:.::|.|:...|:.|
Human   798 KDSGSKDKTSALSLSNV--------AGVFYILVGGLGLAMLVALIEFCYKSRAEAK 845

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.