Protein Alignment Ir75c and Grik4

DIOPT Version :9

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_036704.1
• Gene: Grik4 / 24406
• RGDID: 2734
• Length: 956
• Species: Rattus norvegicus
• Alignment Length: 687
• Identity: 134/687 - (19%)
• Similarity: 237/687 - (34%)
• Gaps: 183/687 - (26%)

  Fly     7 YRLIVFNLLEINLS----------NLMVFHCWSIKEAF--PLVEMLNQ----------------- 42
            |...:|..||.:|.          |::.|..::...||  ...:.|||
  Rat   240 YYTYIFTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFSQSLNQSWQENCDHVPFTGPALS 304

  Fly    43 -----NGIFSQYIDVQNPDNLANVHKEYLDSDLVRLGVFLDLGCDKAELVTNQSSRARLYNQNLH 102
                 :.:::....||.    .|..:|        :|| ..|.|..|::
  Rat   305 SALLFDAVYAVVTAVQE----LNRSQE--------IGV-KPLSCGSAQI---------------- 340

  Fly   103 WLLYDEAGNFTKLTQLFEGANLSLNADVTYVSREDEERFILHDVYNKGSHLGGKLNITVDQTLQC 167
            |.......|:.::.:| ||    |...:.:.|:.....:.|.           .|..|.:...|.
  Rat   341 WQHGTSLMNYLRMVEL-EG----LTGHIEFNSKGQRSNYALK-----------ILQFTRNGFRQI 389

  Fly   168 NRSHCQVKEYLSELHLRPRLQHRMDLSSVTFRLAALVSVLPINSSEEELLEFLNSDRDSHMDSIS 232
            .:.|  |.|.||   :..|| :..::|...|....:|:.:    .|...|....:.:|  |:...
  Rat   390 GQWH--VAEGLS---MDSRL-YASNISDSLFNTTLVVTTI----LENPYLMLKGNHQD--MEGND 442

  Fly   233 RIGN---RLIMHTQEILGF--KLHYIWCGTWSVQDAFG---GAIGMLTNESAELCTTPFVPSWNR 289
            |...   .::....|||.|  |:..:..|.:.|.:|.|   |.:|.|....|:|...
  Rat   443 RYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVA-------- 499

  Fly   290 LHYLHPMTEQAQFRAVCMFRTPH-NAGIKAAV------------FLEPFMPSVWFAFAGLLIFAG 341
                 .:|..|:...|..|..|. ..||....            ||:||.|.||.......:...
  Rat   500 -----GLTITAEREKVIDFSKPFMTLGISILYRVHMGRRPGYFSFLDPFSPGVWLFMLLAYLAVS 559

  Fly   342 VLLWMIFHLERH-WMQ-------RCLDFIP--SLLSSCLISFGAACIQGSYLMPKSAGGRL---- 392
            .:|:::..|..: |..       ||...:.  ||.:|.....|....|||.:.|::...|.
  Rat   560 CVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGV 624

  Fly   393 --AFIAVMLTSFLMYNYYTSIVVSTLLGSPVRSNIRTIQQLAD-SSLDVGFDTVPFTKTYLVSSP 454
              ||..::::|      ||:.:.:.|....:...|.::..||| ::::.|......:.|:..:|.
  Rat   625 WWAFTLIIISS------YTANLAAFLTVQRMEVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSR 683

  Fly   455 RPDIRSLYKQKVESKRDPNSVWLSPEEGVIRVRDQPGFVYTSEASFMYHFVEKHYLPREISDLNE 519
            ....:.::....  .:.|:....|.|||:.|       |..|..:|:.......|..:...:|.:
  Rat   684 YQTYQRMWNYMY--SKQPSVFVKSTEEGIAR-------VLNSNYAFLLESTMNEYYRQRNCNLTQ 739

  Fly   520 IILRPESAVYGM-VHLNSTYRQ----LLTQLQV---------RMLETGITSKQSRFFSKTKLHTF 570
            |....::..||: :.:.|.:|.    .:.|||.         :..|.|...|:....:|
  Rat   740 IGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWWEGGKCPKEEDHRAK------ 798

  Fly   571 SNSFVIQVGMEYAAPLFISLLVAYFLALLILILEICW 607
                  .:|||....:|:.|:....:|:.:.:||..|
  Rat   799 ------GLGMENIGGIFVVLICGLIVAIFMAMLEFLW 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	49/255 (19%)
Grik4	NP_036704.1	Periplasmic_Binding_Protein_type1	24..402	CDD:415822	37/211 (18%)
		PBP2_iGluR_kainate_KA1	415..785	CDD:270442	80/403 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..956

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349666
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840