Protein Alignment Ir75c and glr-6

DIOPT Version :9

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_741822.2
• Gene: glr-6 / 180955
• WormBaseID: WBGene00001617
• Length: 844
• Species: Caenorhabditis elegans
• Alignment Length: 708
• Identity: 134/708 - (18%)
• Similarity: 244/708 - (34%)
• Gaps: 211/708 - (29%)

  Fly     4 WPLYRLIVFNLLEINLSNLMVF------------HCWSIKEAF-PLVEMLNQ---NGIFSQYIDV 52
            ||....:   |:|::.:..:.|            |.|.:..|. .|.:.|:|   ||:....:.|
 Worm   205 WPKKNRV---LIELSPNETLTFFDASLKLGMISVHNWFLITALDDLNDHLSQYTHNGMRVSLLTV 266

  Fly    53 Q----NPDNLA----NVHKEYL------------------DSDLVRLGVFLDLGCDKAELVTNQS 91
            .    |.::||    ::::|||                  ||.|        |.|        |:
 Worm   267 SKEKWNQNDLAIKLPDMYQEYLAKIPSNPRTPFKDFAFIFDSIL--------LAC--------QA 315

  Fly    92 SRARLYNQNLHWLLYDEAGNFTKL--TQLFEGANLSLNADVTYVSREDEERFILH----DVYNKG 150
            ...|:.:..     .:||....||  .:.|:|    |...:::....|.....||    .:...|
 Worm   316 GDRRIISCG-----DNEAVKKFKLPIVKPFKG----LTGKISFNGTSDRSDSELHIWEMGITGAG 371

  Fly   151 SHLG-------GKLNIT-VDQTLQCNRSHCQ--VKE----YLSELHLRP----------RLQHRM 191
            .|.|       |...:| :.:.:.....|.|  |:|    .::.:|.:|          |::|.
 Worm   372 LHTGIWKSTWEGSKELTMLAKNIPGTHEHYQASVRESRTLKVTSIHEKPYVIEKIMPDGRIKHE- 435

  Fly   192 DLSSVTFRLAALVSVLPINSSEEELLEFLNSDRDSHMDSISRIGNRLIMHTQEILGFKLHYIWCG 256
                     ...|.:|      ::|.|.|:.:....:...::.|.|.                .|
 Worm   436 ---------GFCVDLL------DKLAEMLHFNYTLKIVKDNKYGERK----------------NG 469

  Fly   257 TWSVQDAFGGAIGMLTNESAELCTTPFVPSWNRLHYLHPMTEQAQFRAVCMFRTPH-NAGIKAAV 320
            |    |.:.|.||.:....|::...|...:..||..:.......|.....:.|.|: .:......
 Worm   470 T----DEWDGMIGEILRGDADMAVAPITVTATRLEVIDFTDPFLQLGISMLMRQPNPKSSSSLTR 530

  Fly   321 FLEPFMPSVWFAFAGLLIFAGVLLWMI------------FHLERH-WMQRCLDFIPSLLSSCLIS 372
            ||.|...||| .|:.:......||..:            |.::.. |...|:     ||.:   .
 Worm   531 FLWPLSASVW-TFSAIATVITALLVTVAAVLSPKESTAEFKIQNSVWYLVCI-----LLRA---G 586

  Fly   373 FGAACIQGSYLMPKSAGGRLAFIAVMLTSF--LMYNYYTSIVVSTL--------------LGSPV 421
            .|..|          ..|....|:.:..||  ::...||:...:.|              ||:..
 Worm   587 SGYNC----------QAGATRLISAVWWSFTLVLIAQYTANFAALLTVDRKSMPFNSFEELGNQT 641

  Fly   422 RSNIRTIQQLADSSLDVGFDTVPFTKTYLVSSPRPDIRSLYKQKVESKRDPNSVWLSPEEGVIRV 486
            ..|..:|         :|..|:.|.|...:.:    .|.|: ::::| .:|::...:..|||.||
 Worm   642 EYNFGSI---------LGGSTMQFFKYSRIET----FRRLW-ERMQS-AEPSAFVGTNHEGVNRV 691

  Fly   487 RDQPGFVYTSEASFMYHFVEKHYLPREISDLNEIILRPESAVYGM-VHLNSTYRQLLTQLQVRML 550
            .::........|:..|...:...|.|    :..::|  .|..|.: :...|.:|:.||:..:.:.
 Worm   692 LNEKYVFLMESATLDYQVTQNCNLTR----VGNVVL--GSNGYSIALPKGSKWREKLTRQILDLN 750

  Fly   551 ETG-ITSKQSRFFSKTKLHTFSN---SFVIQVGMEYAAPLFISLLVAYFLALLILILE 604
            |.| |...::.::.|::....|:   .....:|.|....||:.|.:...:.:|..:||
 Worm   751 EKGIILMLKNNWWKKSQQECQSSEPEDLQTALGAENVYGLFLLLALGSGIGVLCAVLE 808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	49/254 (19%)
glr-6	NP_741822.2	PBP1_iGluR_non_NMDA-like	21..394	CDD:380591	42/216 (19%)
		PBP2_iGluR_Kainate	409..764	CDD:270432	78/430 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010